2022 Fiscal Year Final Research Report
Prospective epidemiologic study of parechovirus-A3 in Japan
Project/Area Number |
19K17290
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 52050:Embryonic medicine and pediatrics-related
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Research Institution | Niigata University |
Principal Investigator |
Aizawa Yuta 新潟大学, 医歯学系, 助教 (90808453)
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Project Period (FY) |
2019-04-01 – 2023-03-31
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Keywords | パレコウイルス / 敗血症 / 新生児 / 早期乳児 / 疫学 |
Outline of Final Research Achievements |
Our national surveillance network established by this study could reveal national and regional epidemiology of parechovirus-A (PeV-A) infection. The number of the patients with PeV-A infection decreased by coronavirus disease 19 epidemic; however, the number increased after lifting the strict infection control and prevention measures against coronavirus disease 19 in 2022. The phylogenetic analysis revealed that the virus strains during the years 2020-2022 converged into one clade among 3 clades formed by the virus strains in 2019, suggesting virus selection pressure. Furthermore, our findings are publicly open through the website, sharing the updated information to those who do not participate in our study.
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Free Research Field |
小児感染症
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Academic Significance and Societal Importance of the Research Achievements |
敗血症や髄膜脳炎を発症して入院する新生児、生後4か月未満の早期乳児に焦点をあてて、パレコウイルスA感染症患者の入院数の実態を全国的な視点と地域の視点から明らかにした。研究中に新型コロナウイルス感染症の流行が起こったため、様々な感染症の動向がかわる中でパレコウイルスA感染症患者の発生数への影響も明らかにした。さらに、その情報を広く共有することで、研究に参加していない施設や患者にも、適切な診断が行われうるという意味で有益な情報を得られるウェブサイトを作成した。
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