Standardized management of air leakage based on quantification of air leakage by analysis of intrathoracic gas concentration.

2023 Fiscal Year Final Research Report

• Project/Area Number: 19K18228
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 55040:Respiratory surgery-related
• Research Institution: Kindai University
• Principal Investigator: Kusumoto Hidenori 近畿大学, 奈良病院, 講師 (60714904)
• Project Period (FY): 2019-04-01 – 2024-03-31
• Keywords: 術後肺瘻

Outline of Final Research Achievements

The fluorescent method showed that the difference in oxygen concentration in the thoracic cavity between the oxygenated and non-oxygenated state was consistent with the disappearance of the air leakage, confirming that the chest drain could be removed. We also measured the oxygen concentration in the pleural effusion as a simpler method and compared it with the disappearance of air leakage. The oxygen level in the pleural effusion was measured daily, and when it reached 94 ± 22 Torr, air leakage was confirmed to have disappeared and the chest drain could be removed. Although there were various restrictions, this value was considered to be a standard for management of the chest drain.

Free Research Field

呼吸器外科

Academic Significance and Societal Importance of the Research Achievements

肺瘻の有無は胸腔ドレーンからの気泡の消失をもって停止と判断されるが、これには豊富な経験が必要である。そこで、簡便かつ客観的な指標として胸腔内の酸素濃度の推移を計測した。本研究では、酸素吸入時と停止後の胸腔内酸素濃度の差がなくなった時点が肺瘻停止であることを確認し、さらに胸水を用いた研究では酸素濃度が100Torr前後まで低下した時点で胸腔ドレーンを抜去できており再挿入症例はなかった。このことから、胸水中に含まれる酸素濃度が肺瘻停止を判断する客観的な指標になりうると考えられた。