Cohort study to predict mid- to long-term health outcomes based on physical function decline in community-dwelling older adults.

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K18504
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 56020:Orthopedics-related
• Research Institution: Fukushima Medical University
• Principal Investigator: Tominaga Ryoji 福島県立医科大学, 医学部, 博士研究員 (20815170)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 高齢者 / 健康アウトカム / 医療費 / QOL / 片足立ち試験 / 脊柱バランス / 脊柱変形

Outline of Final Research Achievements

Data from a prospective cohort study of community-dwelling residents aged 50 years and older were used for the analysis. Participants who passed the open-eye, single limb standing test at baseline had significantly lower medical costs than those who did not. The mean difference in medical costs between the two groups was US$4,064 (95 % confidence interval: US$2,661-5,467). We also examined the detailed relationship between sagittal balance, which surfaces as an aspect of physical function in the elderly, and pain-specific quality of life measures as health outcomes. of the dose-response relationships for the three sagittal alignment indices and quality of life measures, the compensatory mechanism for abnormal sagittal alignment was found to deteriorate rapidly above a threshold value (PI-LL = 10 °), indicating that compensatory mechanisms for sagittal alignment abnormalities may deteriorate rapidly when the threshold value (PI-LL=10°) is exceeded.

Free Research Field

整形外科

Academic Significance and Societal Importance of the Research Achievements

地域在住高齢者において、静的バランス能力の評価は、将来的に医療サー ビスを頻繁に利用するリスクの高い人を特定するのに有用である可能性が示唆された。また、地域在住高齢者の内、60歳代・80歳代はそれぞれ身体機能測定試験の種類によっては、天井効果・床(底打ち)効果があるため、特定の身体機能測定試験を用いた医療費予測に適した年代は70歳代が妥当である可能性を示唆する知見も得られた。さらに、身体機能の一側面として表面化する脊柱矢状面バランス低下や成人脊柱変形の正確な分類法や治療戦略の確立、ひいては健康アウトカムの予測のために、矢状面アライメントと腰痛特異的QOLの関連性について、有用な知見が得られた。