2021 Fiscal Year Final Research Report
Effect of Colloidal Platinum Nanoparticles on Bonding Performance to Demineralized Dentin and 1 Step Bonding Agent
| Project/Area Number |
19K19003
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 57030:Conservative dentistry-related
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | 白金ナノコロイド / １ステップアドヒーシブ / 脱灰象牙質 |
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| Outline of Final Research Achievements |
The purpose of this study was to evaluate the dentin bond strength for demineralized dentin in resin composite restoration with colloidal platinum nanoparticles (CPN). CPN was used as a pretreatment material for one-step adhesive system, and aimed to obtain long-term adhesive durability.
In short term, both sound and demineralized dentin, the highest bond strength was shown under the condition that 1% CPN and phosphoric and were mixed (phosphoric acid concentration 35%), applied for 1 second and washed with water. Also in long term data showed high bond strength when CPN was used. Resin-dentin interfaces were observed using a scanning electron microscope.
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| Free Research Field |
歯科保存修復学
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| Academic Significance and Societal Importance of the Research Achievements |
現在高齢化が年々進み、歯科の疾患構造も変化し在宅での治療頻度が増し、根面う蝕などによる脱灰象牙質を残置せざるを得ない状況が増加している。しかし、脱灰象牙質への効果的な接着方法については未だ明らかになっていない。本研究では抗菌タンパクの誘導能を認める白金ナノコロイドを用いて歯質接着性の改善と最新の歯科材料への臨床応用を目的とした。その結果、白金ナノコロイドを現代の臨床で使用頻度の高い１ステップアドヒーシブの前処理剤として用いると健全・脱灰象牙質のいずれにも良好な接着強さを示すことが判明した。このことは歯質接着分野に、ナノテクノロジーの応用として白金ナノコロイドが大きく貢献する可能性を示している。
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