2022 Fiscal Year Final Research Report
The research aimed for establishing the guidelines of removable partial dentures for patients with diabetes mellitus
| Project/Area Number |
19K19085
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 57050:Prosthodontics-related
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| Research Institution | Showa University (2020-2022)
Tokyo Medical and Dental University (2019) |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2023-03-31
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| Keywords | 部分床義歯 / 2型糖尿病 |
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| Outline of Final Research Achievements |
This study aimed to evaluate the abutment survivals and surrounding periodontal tissues of removable partial dentures (RPDs) in patients with type 2 diabetes mellitus (T2DM). Regardless of T2DM, RPDs with rigid retainers and major connectors could prevent the progression of periodontal disease, and successfully maintained most of the abutment teeth during 5-years SPT. However, T2DM may be significantly associated with the loss of bone height reduction and density on the side of the denture base area. Further basic research on bone dynamics under denture base was considered necessary. In addition, the impact of the other factors on the long-term survival of abutment teeth was estimated using a multivariate Cox regression model considering multicollinearity.
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| Free Research Field |
歯科補綴学
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| Academic Significance and Societal Importance of the Research Achievements |
超高齢社会において全身疾患を有する患者の割合は年々増加しているが，そのような患者へ提供できる補綴治療のエビデンスはまだ少ない．本課題で得られた知見は，現在国内で増加している2型糖尿病患者の補綴治療の方針立案時のエビデンスを提供するものであり，将来的に有病者の補綴指針の一助になる可能性がある．
また採集したデータによる回帰分析から導いた支台歯の長期生存に関する予測因子は，補綴装置設置後の効果的で安全性の高い治療方針を担保するための重要な情報となり，高齢者を中心とした多くの国民に安全な医療と口腔の健康増進をもたらすと考える．
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