Development of a novel mandibular condylar fracture treatment plate using bioresorbable material

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K19158
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 57060:Surgical dentistry-related
• Research Institution: Okayama University
• Principal Investigator: Sukegawa Shintaro 岡山大学, 歯学部, 客員研究員 (20837661)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 下顎骨関節突起骨折 / 観血的整復固定術 / 生体吸収性プレート

Outline of Final Research Achievements

In recent years, open reduction and fixation using a titanium miniplate has been performed for the treatment of mandibular condylar fractures, but the miniplate ultimately requires plate removal. Therefore, in recent years, the selection of bioresorbable plates has been considered. The applicant has previously reported a highly biocompatible material consisting of a composite of poly-L-lactic acid (PLLA) and uncalcined hydroxyapatite (u-HA), and has also demonstrated intramaxillary fixation of a similar bioresorbable plate. have reported the usefulness of This plate is expected to have new applications and uses for mandibular condylar fractures. Therefore, in this research project, we will verify the required strength of the mandibular condylar fracture treatment plate, and further confirm the biocompatibility and safety.

Free Research Field

歯科口腔外科

Academic Significance and Societal Importance of the Research Achievements

本プレート開発は、下顎骨関節突起骨折への新たな応用・使用が期待できたものである。そこで本研究課題では、生体吸収性下顎骨関節突起骨折治療用プレートの必要強度を検証し、さらに生体検証による有用性、安全性を 確認する。これにより、骨伝導性を有しさらに完全に生体内で吸収分解することで再度プレート摘出手術を必要としない大きな長所を備えた生体吸収性プレート の使用が可能となり患者の精神的、肉体的負担の軽減や医療費削減にも大きく役立つと考えられる。