2021 Fiscal Year Final Research Report
Construction of regional medical cooperation system for appropriate use of outpatients oral antimicrobial agents
Project/Area Number |
19K19356
|
Research Category |
Grant-in-Aid for Early-Career Scientists
|
Allocation Type | Multi-year Fund |
Review Section |
Basic Section 58010:Medical management and medical sociology-related
|
Research Institution | Kochi University |
Principal Investigator |
Yagi Yusuke 高知大学, 医学部附属病院, 薬剤師 (30717351)
|
Project Period (FY) |
2019-04-01 – 2022-03-31
|
Keywords | 外来経口抗菌薬 / 抗菌薬使用密度 / 抗菌薬使用日数 / 薬剤費 / 抗菌薬適正使用 / 経口用レボフロキサシン / 感染防止対策加算 / 地域医療連携 |
Outline of Final Research Achievements |
By creating and disseminating guide for the proper use of outpatients antimicrobial agents, Kochi Medical School Hospital was able to reduce the amount of outpatients oral antimicrobial agents used, the number of days of use, and drug costs over time, and correct improper use. In addition, it was found that the amount of oral levofloxacin used, which is feared to become resistant to Streptococcus pneumoniae, was biased depending on the region, and the amount of oral levofloxacin used in Kochi prefecture as a whole decreased with the utilization of guide and enlightenment of proper use. Based on the results of this research, strengthening regional medical cooperation such as grasping trends in antimicrobial agents use and using guidance throughout Kochi prefecture will lead to further reductions in the amount of oral antimicrobial agents used as well as levofloxacin. It was thought to help control antimicrobial resistant bacteria.
|
Free Research Field |
医療薬学
|
Academic Significance and Societal Importance of the Research Achievements |
日本政府は抗菌薬の耐性化防止対策として適正な抗菌薬使用による使用量の抑制を国家戦略として実施している。本研究結果では、自院で作成した外来抗菌薬適正使用の手引きの活用と高知県全体での抗菌薬使用動向の把握および地域医療連携の強化により、外来での経口用抗菌薬の使用量と薬剤費削減ができることを明らかにした。このことは、抗菌薬使用量を削減し耐性化を抑制することで、感染症治療の難渋化や死亡率の増加および医療費増大といった社会全体への不利益の回避に寄与できる可能性がある。
|