Investigation of the actual situation of recanalization treatment and data feedback effect using the Japan Stroke Data Bank

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K19373
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58010:Medical management and medical sociology-related
• Research Institution: National Cardiovascular Center Research Institute
• Principal Investigator: Sonoda Kazutaka 国立研究開発法人国立循環器病研究センター, 病院, 客員研究員 (60791829)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 急性期脳梗塞 / 再開通治療 / tPA / 血栓回収術 / QI

Outline of Final Research Achievements

We examined the actual practice and impact of intravenous tPA and endovascular revascularization for acute cerebral infarction in Japan, and found that for intravenous tPA, the rate of tPA administration for acute cerebral infarction increased over time and functional outcomes improved over time. Regarding endovascular recanalization, the study also found that the use of endovascular revascularization therapy increased, especially in more severely injured patients and favorable outcomes increased significantly over time, but decreased in patients with a minor illness. It is difficult to verify at this time whether notification of the achievement status of QI items to each facility has an effect on the actual practice status, and more information needs to be accumulated over time.

Free Research Field

急性期脳梗塞

Academic Significance and Societal Importance of the Research Achievements

ｔPA静注療法及び、血管内再開通治療は急性期脳梗塞に対する現在の根幹となる治療である。これらの治療について、これまで本邦における全国的な実態は不明であり、これが明らかとなることで、今後の脳卒中診療行政に資することが期待される。また、本研究内容を含む日本脳卒中データバンクの解析結果は書籍として販売されており、医療者、行政者のみならず、一般の国民に対しても啓蒙となる。