Development of the early detection method of ICU-AW using abdominal CT images

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K19577
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58060:Clinical nursing-related
• Research Institution: International University of Health and Welfare (2020-2021); Teikyo University (2019)
• Principal Investigator: Miotbe Yuta 国際医療福祉大学, 大学院, 講師 (10772915)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: ICU-AW / CT画像 / 骨格筋 / 集中治療

Outline of Final Research Achievements

The present study assessed the effectiveness of SMI, as measured by abdominal CT scans, in predicting the onset of ICU-AW in patients with sepsis admitted to the ICU.Patients were retrospectively divided into two groups by MRC score at ICU discharge: Group AW comprised patients with an MRC score <48, and Group NAW comprised the remaining patients. SMI was significantly lower in Group AW than in Group NAW (p < 0.05). ROC analysis revealed that the cut-off value of SMI for predicting ICU-AW was 44.1, and the multivariate analysis revealed that only low SMI was a significant factor in predicting ICU-AW (p <0.05). Our results show that SMI measurement at ICU admission is a valid predictive factor for ICU-AW progression in septic patients.

Free Research Field

集中治療看護

Academic Significance and Societal Importance of the Research Achievements

ICU-AWの診断が早期に行うことができれば、早期から離床訓練の実施および強化や鎮静剤のコントロール等を行うことができる。だが、ICUに入室した患者の多くは定められたプロトコールに沿って早期離床訓練が行われ個別性に合わせて行われていない。我々の研究はICU入室した敗血症患者に対し腹部CTを用いて骨格筋断面積とMRCスコアとの関連を明らかにし、早期にICU-AWを診断することである。早期にICU-AWを診断することができれば、離床訓練の早期介入および強化を行うことができ、ICU退室後の患者のADLおよびQOLを向上させることができると考える。