Survey on anticancer drug (CPM) exposure to pediatric patients with cancer and their family caregivers.

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K19594
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58060:Clinical nursing-related
• Research Institution: Daiichi University, College of Pharmaceutical Sciences (2021-2022); Fukuoka Nursing College (2019-2020)
• Principal Investigator: Noda Yuko 第一薬科大学, 看護学部, 助教 (60824513)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 抗がん剤曝露 / 小児がん患児。加速

Outline of Final Research Achievements

This study aimed to determine the actual exposure of pediatric cancer patients and their accompanying family caregivers to anticancer agents, and to develop guidelines for reducing exposure to family caregivers. Cyclophosphamide was detected in the urine and aprons, and gloves worn by family members during defecation and oral care. High levels of cyclophosphamide were also detected in gauze underwear worn by affected children on all survey days. It was suggested that emotional care, such as holding, playing, and touching, could affect the exposure of family caregivers, particularly if personal protective equipment was not adequately worn, and care was prolonged. The study results were presented at national scientific meetings and in Pediatric Blood & Cancer journal.

Free Research Field

看護

Academic Significance and Societal Importance of the Research Achievements

本研究は、小児がん患児やその家族に対する抗がん剤曝露の実態を明らかにし、家族の健康に関連する問題に取り組み、家族の曝露を減らすためのガイドラインの開発に貢献し得るものとなったと考える。また、本研究結果に基づき、小児がん医療に携わる医療従事者がより適切な安全対策を講じることができるようになると考えらる。よって、本研究は社会的にも意義のあるものであり、小児がん医療の質向上に貢献するものと考えられる。