Development of treatment assist system for spinal cord disease

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K20675
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 90110:Biomedical engineering-related
• Research Institution: Yamaguchi University
• Principal Investigator: Nishida Norihiro 山口大学, 医学部附属病院, 助教 (90535262)
• Project Period (FY): 2019-04-01 – 2021-03-31
• Keywords: バイオメカニクス / 有限要素法 / 医工連携

Outline of Final Research Achievements

With the cooperation of the Faculty of Veterinary Medicine of Yamaguchi University and meat suppliers, we have conducted velocity-dependent, anisotropic and compression tests on biological tissues. Based on these experiments, we are currently establishing a technique to obtain physical property data that can be reflected in simulation software, and we are verifying the clinical application of simulation analysis.
Simulation: Spinal cord and spine simulation analysis from medical images of actual clinical cases, and instructed two orthopedic surgery graduate students and a graduate student studying in Japan in the Department of Orthopedic Surgery at Iwate Medical University. We conducted joint research with Terumo Corporation, Tanac Corporation, Mazda Motor Corporation, and JSOL Corporation as the principal investigator.

Free Research Field

脊椎脊髄疾患

Academic Significance and Societal Importance of the Research Achievements

肩・膝関節など骨成分が主な組織では、動物やご遺体を使用した組織の物性実験や、シミュレーションでは人工関節、靭帯の解析など有限要素法解析の論文数は増加している。しかし、脊髄脊椎疾患では、脊髄や脊椎周囲組織の個人差を考慮した組織の物理学的強度を解明する研究や、医用画像から様々な脊椎シミュレーションシステムまで応用を目指す研究は行われておらず、学術的意義が高い。本研究は多数の脊髄脊椎症例と、ヒト・動物の組織の物性実験と医用画像データを用いたシミュレーションを組み合わせる非常にユニークな医工獣産学連携研究である。