2021 Fiscal Year Final Research Report
Development of Quick Microvascular Anastomotic Device via Electrocautery Welding of Vascular Wall
Project/Area Number |
19K20678
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 90110:Biomedical engineering-related
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Research Institution | Tohoku Medical and Pharmaceutical University |
Principal Investigator |
Tachi Kazufumi 東北医科薬科大学, 医学部, 講師 (40377544)
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Project Period (FY) |
2019-04-01 – 2022-03-31
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Keywords | マイクロサージャリー / 微小血管吻合 / 血管吻合器 / デバイス / 機械 / 溶接 / 電気凝固 / 血管吻合 |
Outline of Final Research Achievements |
We developed prototypes of microvascular anastomotic device which connect(anastomose) a couple of vascular vessels by welding the vessels' stumps through electrocoagulation given by high frequency generator. By doing so, we assumed that microvascular anastomosis which usually is performed under operative microscope by a skilled surgeon using micro-needle-strings with long operating time and massive effort, would be more easily and promptly performed using the device. Firstly, we made forceps-type prototypes to evaluate the strength of the anastomosis; then made ring-type prototypes with different forms of metallic parts through which the electricity passes achieving welding of the two vessels. Results: large area of the vessel wall was damaged while the electricity generated heat which led to boiling of the vessel walls. The strength of the anastomosis performed by the device was not enough to prevent the two vessels to take apart. Further improvement is needed.
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Free Research Field |
マイクロサージャリー,創傷外科
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Academic Significance and Societal Importance of the Research Achievements |
本研究は現在多くの組織移植で使われているマイクロサージャリー分野の手技である微小血管吻合をデバイスで自動化することを目的とする.微小血管吻合は通常,顕微鏡下でトレーニングを積んだ外科医が小さい針糸を使用して縫合することで行われる.我々は,血管断端を電気で通電することで血管同士を「溶接」し,この手技を機械によって自動化することを考案した.口径3mm程度の動物の血管を対象に試作品を作り,吻合実験を行ったが.血管吻合は達成されたものの,熱が不必要な範囲の血管にまで及んでしまったり,強度が不十分であったりする結果となった.デバイスの素材や,血管の水分含有量などを更に詳細に調べる必要がある.
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