2021 Fiscal Year Final Research Report
Development of MRI-based theranostic nanomedicines
| Project/Area Number |
19K20693
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 90120:Biomaterials-related
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| Research Institution | National Defense Medical College |
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Principal Investigator |
Yamada Naoki 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 生理学, 助教 (00837370)
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | 高分子 / 薬物送達システム |
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| Outline of Final Research Achievements |
This study was aimed at the development of a novel theranostic nanomedicine. For this purpose, we first synthesized biocompatible copolymer of a poly(ethylene glycol) and polylysine through phosgene-free methods. However, further investigation of probe molecules is needed.
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| Free Research Field |
薬物送達システム
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| Academic Significance and Societal Importance of the Research Achievements |
本研究によりナノメディシンの薬効の事前予測が可能となれば、ナノメディシンの個別化医療につながる。本研究期間中にはナノメディシンの構造最適化までは至らなかったものの、候補となる化学構造は見出しており、引き続き検討を行っていく。
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