The research and development of a novel remote-monitoring electrocardiograph with a flexible thin sensor sheet

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K20710
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 90130:Medical systems-related
• Research Institution: Osaka University
• Principal Investigator: Sho Murase 大阪大学, 医学系研究科, 招へい教員 (30762538)
• Project Period (FY): 2019-04-01 – 2021-03-31
• Keywords: パッチ型心電計 / 多電極 / 心房細動 / 脳梗塞

Outline of Final Research Achievements

We developed the prototype of a novel multi-electrode patch cardiograph with a flexible thin sensor sheet. The device had the equivalent performances as the conventional 12-lead electrocardiograph in measuring adult normal cardiograms and rendering their waveforms. We improved each components of the prototype and repeated confirming the operation, and the upgraded prototype was able to continuously measure long-term electrocardiograms in a small number of patients with acute ischemic stroke. We aim to lead to clinical trials targeting larger population in the future.

Free Research Field

脳卒中

Academic Significance and Societal Importance of the Research Achievements

本研究助成により、フレキシブル薄膜センサーという新規技術を用いた多電極パッチ型心電計の試作機を導出することができた。心房細動などの不整脈を検出する上で、本研究内容は次世代の革新的な心電図継続システムの骨格となり得ると考えられる。より大規模な集団に対して試験的臨床使用を重ねることで、各構成要素の更なる改良を進め、長時間心電図を測定する上での欠点であった、装着不快感、日常生活制限、医療機関受診の必要性などを解消しうるデバイス開発へと繋げていく。