2019 Fiscal Year Final Research Report
Establishment of the nasal airway obstruction improvement method of children with cleft lip and palate using the fluid analysis
Project/Area Number |
19K21399
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Project/Area Number (Other) |
18H06312 (2018)
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Multi-year Fund (2019) Single-year Grants (2018) |
Review Section |
0907:Oral science and related fields
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Research Institution | Kagoshima University |
Principal Investigator |
Ban Yusuke 鹿児島大学, 医歯学域鹿児島大学病院, 助教 (60827294)
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Project Period (FY) |
2018-08-24 – 2020-03-31
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Keywords | 小児 / OSA / 流体解析 / 呼吸 |
Outline of Final Research Achievements |
This study evaluated RME induced changes in ventilation parameters in children with UCLP using computational fluid dynamics. Setting and Sample Population: Nineteen patients (10 boys, mean age 10.7years) who required RME had cone‐beam computed tomography images taken before and after RME. Methods: Nasal airway ventilation parameters were analysed via computational fluid dynamics, and nasal cross‐sectional area (CSA) was measured. Results: Maximum pressure, velocity and nasal resistance were significantly reduced by RME in the UCLP group. Air flow rate and CSA on the cleft side significantly were increased by RME in the UCLP group. Conclusions: In children with UCLP, increasing the quantity of airflow and CSA on the cleft side by RME substantially improved nasal ventilation
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Free Research Field |
小児歯科
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Academic Significance and Societal Importance of the Research Achievements |
口唇口蓋裂児(CLP児)には審美・哺乳・咀嚼・言語等の多職種医療従事者の成育的支援が実践されている。しかし、CLP児の約30%が閉塞性睡眠時無呼吸症候群(OSAS)に罹患していると報告されているにもかかわらず、呼吸の面からの支援は十分とはいえない。しかし、本研究で、SASは鼻腔から下咽頭までの上気道のあらゆる部位が原因となり発症する。その罹患率は定型発達児で2%とされている一方、CLP児は30%と著しく高いことから、OSASの主な原因部位として鼻腔が考えられ、その治療方法としてRMEの有効性が示され、歯科からの睡眠医療への貢献が期待される
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