The Effect of Pregnancy Anemia Prophylaxis by Continuous Non-invasive Hemoglobin Measurement

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K21462
• Project/Area Number (Other): 18H06381 (2018)
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund (2019); Single-year Grants (2018)
• Review Section: 0908:Society medicine, nursing, and related fields
• Research Institution: Fujita Health University
• Principal Investigator: Shimizu Mikiko 藤田医科大学, 保健衛生学部看護学科, 講師 (90402627)
• Project Period (FY): 2018-08-24 – 2023-03-31
• Keywords: 貧血 / 妊婦 / ヘモグロビン / 経皮的 / 非侵襲的 / 鉄摂取量 / 胎児発育不全 / 吸光度

Outline of Final Research Achievements

We did not find it necessary to develop an algorithm correction equation for the Pronto-7(Masimo Japan) transcutaneous hemoglobin measuring device by specific relative diffuse reflectance spectra of blood concentration in pregnant women. However, it is necessary to revalidate the algorithm with an increased sample size.
Pregnant women measured hemoglobin levels at least once a week in an environment where noninvasive/transcutaneous hemoglobin measurement was available close at hand at home. They often took measurements on their days off, and their voluntary behavior of taking measurements when they had time was observed, which was predicted to increase their awareness of anemia. This suggests that it is possible to construct a system in which pregnant women can check their anemia by taking measurements on their own during their waiting time by installing the equipment in obstetric outpatient clinics.

Free Research Field

母性看護学

Academic Significance and Societal Importance of the Research Achievements

本研究では、先行研究を基に妊娠による血液の生理学的変化に着目して見出した特異的な相対拡散反射スペクトルを追究し、非侵襲的／経皮的ヘモグロビン測定機器Pronto-7（マシモジャパン社）のアルゴリズムの補正式の必要性はないという一定の成果を得た。
産科外来に非侵襲的／経皮的ヘモグロビン測定機器を設置し、待ち時間を利用して、妊婦が自ら測定をして貧血チェックすることによる貧血予防／改善システム構築の可能性が示唆された。このシステム構築は妊娠貧血による胎児発育不全の予防に繋がり、その社会的意義は大きい。