2019 Fiscal Year Final Research Report
Chemometric approach to development of indicators for "toxic unknowns" in municipal wastewater
| Project/Area Number |
19K21556
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| Project/Area Number (Other) |
18H06493 (2018)
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Multi-year Fund (2019)
Single-year Grants (2018) |
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| Review Section |
1101:Environmental analyses and evaluation, environmental conservation measure and related fields
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2018-08-24 – 2020-03-31
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| Keywords | 未規制化学物質 / Elastic net回帰 / 細胞毒性試験 / EEM |
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| Outline of Final Research Achievements |
Comprehensive evaluation of effluent toxicity regardless of individual chemicals and development of rapid detection method of causative agents are necessary to further expand water reuse system. In this study, water quality analysis and cytotoxicity test were conducted for wastewater samples with various compositions, and those parameters affected cytotoxicity was investigated by chemometric approach. The Elastic net regression analysis using 208 datasets estimated 16 water quality parameters which contributed increase in cytotoxicity. The estimated parameters related to fluorescence character suggested a possibility that hydrophobic dissolved organic matters with relatively high molecular weight were involved in the appearance of cytotoxicity.
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| Free Research Field |
環境工学
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| Academic Significance and Societal Importance of the Research Achievements |
都市下水は，身近に存在し，天候に左右されにくい水資源として世界各地で活用が進められている。本研究の成果は，下水試料中の未知毒性物質群を簡便・迅速に特定しうる管理指標の開発を推進するために必要な基礎的知見を提供する。このことは，下水再利用システムにおける健康リスク低減ならびにシステム管理の効率化に資するものである。
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