The elucidation of change of oral ecosystem including dynamics of microbiome by orthodontic treatment and building a new prevention system

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K24121
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0907:Oral science and related fields
• Research Institution: Hiroshima University
• Principal Investigator: Kado Isamu 広島大学, 医系科学研究科(歯), 助教 (50846847)
• Project Period (FY): 2019-08-30 – 2022-03-31
• Keywords: 矯正歯科治療 / 細菌

Outline of Final Research Achievements

This study reveals some of the dynamics of the bacteria that live in the mouth of patients undergoing orthodontic treatment to improve malocclusion. Specifically, when the fixed orthodontic appliance was attached to the surface of teeth, the bacteria that cause periodontitis tend to be dominant. It was also clarified that not only bacteria but also various things such as the amount of saliva and whether the environment is prone to tooth decay differ depending on gender and age. These may help prevent tooth decay and periodontal disease in patients undergoing orthodontic treatment.

Free Research Field

矯正歯科学

Academic Significance and Societal Importance of the Research Achievements

本研究は、唾液やプラークを採取し、その量や性質を分析することで行われました。細菌学的な分析には次世代シークエンサーを使用し、菌種を特定せず網羅的に解析しました。矯正歯科治療を受けている患者を対象とした研究では、この手法を用いたものはまだ少ないため、高い学術的価値を有すると考えられます。