Extracting characteristics of older adults living in the community for tailored intervention to prevent dementia

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K24188
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0908:Society medicine, nursing, and related fields
• Research Institution: National Center for Geriatrics and Gerontology
• Principal Investigator: Katayama Osamu 国立研究開発法人国立長寿医療研究センター, 老年学・社会科学研究センター, 研究員 (60845999)
• Project Period (FY): 2019-08-30 – 2021-03-31
• Keywords: 軽度認知障害 / ライフスタイル / 認知症 / 危険因子

Outline of Final Research Achievements

We determined the changes in lifestyle activity patterns and patterns of possessing modifiable risk factors of dementia among older adults with mild cognitive impairment (MCI). The reverters maintained multidomain lifestyle activities, converters discontinued multidomain lifestyle activities or were inactive, and maintainers maintained productive activities. The possession patterns of modifiable risk factors among the older adults with MCI were classified into five patterns: low risk, psychosocial, health behavior, educational, and smoking factors. According to the logistic regression analysis, the activity patterns of those who continued to engage in multidomain lifestyle activities and start activities, were more likely to help in reverting from MCI to normal cognition.

Free Research Field

老年医学

Academic Significance and Societal Importance of the Research Achievements

MCIを有する高齢者のライフスタイル活動パターンや認知症の修正可能な危険因子の保有パターンと正常な認知機能への回復との関連を明らかにしたことが学術的意義といえる。本研究成果の社会的意義は、臨床医をはじめとするMCIを有する高齢者に関わる者が日々の診療等で高齢者のライフスタイル活動パターンや認知症の修正可能な危険因子の保有パターンを評価し、高齢者中心のテーラード介入を実践することがMCI者の認知機能の回復につながる可能性があることを示唆したことといえる。