The Effect of Oral or Skin intake of Vitamin D on Locomotor

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K24226
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Multi-year Fund
• Review Section: 0908:Society medicine, nursing, and related fields
• Research Institution: Nagoya University
• Principal Investigator: Makida Kazuya 名古屋大学, 医学部附属病院, 医員 (10843352)
• Project Period (FY): 2019-08-30 – 2022-03-31
• Keywords: ビタミンD / 紫外線 / 骨粗鬆症 / サルコペニア / 地域住民コホート研究

Outline of Final Research Achievements

According to their living conditions and questionnaires, Participants in the study were divided into two groups: those who received more vitamin D from their diet and those who received more vitamin D from their skin due to ultraviolet radiation. There was no difference in blood vitamin D levels between the two groups. There were also no differences between the two groups in terms of musculoskeletal diseases such as osteoporosis, fractures, osteoarthritis, and locomotive syndrome. The group that produced vitamin D from the skin by ultraviolet radiation had greater muscle strength and muscle mass and lower body fat percentage.

Free Research Field

整形外科学

Academic Significance and Societal Importance of the Research Achievements

本研究の結果から、同じ血液中のビタミンDの値であっても、ビタミンDを紫外線により皮膚で産生する経路の方が、ビタミンDを食事から摂取する経路よりも、筋力・筋量に対して良い影響を与えている可能性が示唆された。
更に研究を進め、ビタミンDの摂取経路と運動器疾患への影響を明らかにすることが、国民に対しより良いビタミンDの摂取方法の提案し、健康増進へ寄与することにつながる。