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2020 Fiscal Year Research-status Report

Reduction of death from colorectal cancer with help of artificial intelligence

Research Project

Project/Area Number 19KK0421
Research InstitutionShowa University

Principal Investigator

森 悠一  昭和大学, 医学部, 講師 (20459209)

Project Period (FY) 2019 – 2021
Keywords人工知能
Outline of Annual Research Achievements

本国際研究では、人工知能(AI)を利用した大腸内視鏡検査により、「命を救える」ことを証明する。共同研究者である三澤将史らが中心となって開発した内視鏡用AIは内視鏡検査中に大腸ポリープ等を自動で検出し、医師の見落としを予防することが期待されている(Misawa M, Kudo S, Mori Y, et al. Gastroenterology 2018)。このAIによって、将来の癌死が実際に抑制できるかどうかを検証することが、本研究の目的である。
本年度は、研究のインフラストラクチャーを構築とするとともに、公的癌検診プログラムとの相談をすすめ、研究のfeasibilityについての検証を徹底的に行った。また、並行してAIのもつ癌死抑制効果の可能性をmicrosimulation modelを用いて検証した。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

当初の予定どおり、研究のインフラ構築が順調にすすんでおり、feasibilityの評価もできた。

Strategy for Future Research Activity

R3年度は、癌検診プログラムとの交渉をはじめる。また、R2年度に実施したmicrosimulation model研究の結果、必要とされるサンプルサイズが大幅に増加する見通しであり、どのようにしてfeasibleな試験を実施しうるかの検討を徹底的に実証する。

  • Research Products

    (16 results)

All 2021 2020

All Journal Article (16 results) (of which Int'l Joint Research: 8 results,  Peer Reviewed: 14 results)

  • [Journal Article] Artificial Intelligence System to Determine Risk of T1 Colorectal Cancer Metastasis to Lymph Node2021

    • Author(s)
      Kudo Shin-ei、Ichimasa Katsuro、Villard Benjamin、Mori Yuichi、Misawa Masashi、et al.
    • Journal Title

      Gastroenterology

      Volume: 160 Pages: 1075~1084.e2

    • DOI

      10.1053/j.gastro.2020.09.027

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] AI everywhere in endoscopy, not only for detection and characterization2021

    • Author(s)
      Hassan Cesare、Mori Yuichi、Antonelli Giulio
    • Journal Title

      Endoscopy International Open

      Volume: 09 Pages: E627~E628

    • DOI

      10.1055/a-1373-4799

    • Int'l Joint Research
  • [Journal Article] Artificial intelligence in colonoscopy ‐ Now on the market. What's next?2021

    • Author(s)
      Mori Yuichi、Neumann Helmut、Misawa Masashi、Kudo Shin‐ei、Bretthauer Michael
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 36 Pages: 7~11

    • DOI

      10.1111/jgh.15339

    • Int'l Joint Research
  • [Journal Article] Charting a path forward for clinical research in artificial intelligence and gastroenterology2021

    • Author(s)
      Glissen Brown Jeremy R.、Waljee Akbar K.、Mori Yuichi、Sharma Prateek、Berzin Tyler M.
    • Journal Title

      Digestive Endoscopy

      Volume: - Pages: -

    • DOI

      10.1111/den.13974

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Development of a computer-aided detection system for colonoscopy and a publicly accessible large colonoscopy video database (with video)2021

    • Author(s)
      Misawa Masashi、Kudo Shin-ei、Mori Yuichi、Hotta Kinichi、Ohtsuka Kazuo、Matsuda Takahisa、Saito Shoichi、Kudo Toyoki、Baba Toshiyuki、Ishida Fumio、Itoh Hayato、Oda Masahiro、Mori Kensaku
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 93 Pages: 960~967.e3

    • DOI

      10.1016/j.gie.2020.07.060

    • Peer Reviewed
  • [Journal Article] Establishing key research questions for the implementation of artificial intelligence in colonoscopy: a modified Delphi method2020

    • Author(s)
      Ahmad Omer F.、Mori Yuichi、et al.
    • Journal Title

      Endoscopy

      Volume: - Pages: -

    • DOI

      10.1055/a-1306-7590

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Current status and future perspective on artificial intelligence for lower endoscopy2020

    • Author(s)
      Misawa Masashi、Kudo Shin‐ei、Mori Yuichi、Maeda Yasuharu、Ogawa Yushi、Ichimasa Katsuro、Kudo Toyoki、Wakamura Kunihiko、Hayashi Takemasa、Miyachi Hideyuki、Baba Toshiyuki、Ishida Fumio、Itoh Hayato、Oda Masahiro、Mori Kensaku
    • Journal Title

      Digestive Endoscopy

      Volume: 33 Pages: 273~284

    • DOI

      10.1111/den.13847

    • Peer Reviewed
  • [Journal Article] Can artificial intelligence help to detect dysplasia in patients with ulcerative colitis?2020

    • Author(s)
      Maeda Yasuharu、Kudo Shin-ei、Ogata Noriyuki、Misawa Masashi、Mori Yuichi、Mori Kensaku、Ohtsuka Kazuo
    • Journal Title

      Endoscopy

      Volume: - Pages: -

    • DOI

      10.1055/a-1261-2944

    • Peer Reviewed
  • [Journal Article] Robust endocytoscopic image classification based on higher-order symmetric tensor analysis and multi-scale topological statistics2020

    • Author(s)
      Itoh Hayato、Nimura Yukitaka、Mori Yuichi、Misawa Masashi、Kudo Shin-Ei、Hotta Kinichi、Ohtsuka Kazuo、Saito Shoichi、Saito Yutaka、Ikematsu Hiroaki、Hayashi Yuichiro、Oda Masahiro、Mori Kensaku
    • Journal Title

      International Journal of Computer Assisted Radiology and Surgery

      Volume: 15 Pages: 2049~2059

    • DOI

      10.1007/s11548-020-02255-3

    • Peer Reviewed
  • [Journal Article] Artificial intelligence for polyp detection during colonoscopy: a systematic review and meta-analysis2020

    • Author(s)
      Barua Ishita、Vinsard Daniela Guerrero、Jodal Henriette C.、L?berg Magnus、Kalager Mette、Holme ?yvind、Misawa Masashi、Bretthauer Michael、Mori Yuichi
    • Journal Title

      Endoscopy

      Volume: 53 Pages: 277~284

    • DOI

      10.1055/a-1201-7165

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Machine learning in GI endoscopy: practical guidance in how to interpret a novel field2020

    • Author(s)
      van der Sommen Fons、de Groof Jeroen、Struyvenberg Maarten、van der Putten Joost、Boers Tim、Fockens Kiki、Schoon Erik J、Curvers Wouter、de With Peter、Mori Yuichi、Byrne Michael、Bergman Jacques J G H M
    • Journal Title

      Gut

      Volume: 69 Pages: 2035~2045

    • DOI

      10.1136/gutjnl-2019-320466

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] How Far Will Clinical Application of AI Applications Advance for Colorectal Cancer Diagnosis?2020

    • Author(s)
      Mori Yuichi、Kudo Shin-ei、Misawa Masashi、Takeda Kenichi、Kudo Toyoki、Itoh Hayato、Oda Masahiro、Mori Kensaku
    • Journal Title

      Journal of the Anus, Rectum and Colon

      Volume: 4 Pages: 47~50

    • DOI

      10.23922/jarc.2019-045

    • Peer Reviewed
  • [Journal Article] Proceedings from the First Global Artificial Intelligence in Gastroenterology and Endoscopy Summit2020

    • Author(s)
      Parasa Sravanthi、Wallace Michael、Bagci Ulas、Antonino Mark、Berzin Tyler、Byrne Michael、Celik Haydar、Farahani Keyvan、Golding Martin、Gross Seth、Jamali Vafa、Mendonca Paulo、Mori Yuichi、et al.
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 92 Pages: 938~945.e1

    • DOI

      10.1016/j.gie.2020.04.044

    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Cost savings in colonoscopy with artificial intelligence-aided polyp diagnosis: an add-on analysis of a clinical trial (with?video)2020

    • Author(s)
      Mori Yuichi、Kudo Shin-ei、East James E.、Rastogi Amit、Bretthauer Michael、Misawa Masashi、Sekiguchi Masau、Matsuda Takahisa、Saito Yutaka、Ikematsu Hiroaki、Hotta Kinichi、Ohtsuka Kazuo、Kudo Toyoki、Mori Kensaku
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 92 Pages: 905~911.e1

    • DOI

      10.1016/j.gie.2020.03.3759

    • Peer Reviewed
  • [Journal Article] Can artificial intelligence standardise colonoscopy quality?2020

    • Author(s)
      Mori Yuichi、Kudo Shin-ei、Misawa Masashi
    • Journal Title

      The Lancet Gastroenterology & Hepatology

      Volume: 5 Pages: 331~332

    • DOI

      10.1016/S2468-1253(19)30407-8

    • Peer Reviewed
  • [Journal Article] Artificial Intelligence-assisted System Improves Endoscopic Identification of Colorectal Neoplasms2020

    • Author(s)
      Kudo Shin-ei、Misawa Masashi、Mori Yuichi、et al.
    • Journal Title

      Clinical Gastroenterology and Hepatology

      Volume: 18 Pages: 1874~1881.e2

    • DOI

      10.1016/j.cgh.2019.09.009

    • Peer Reviewed

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Published: 2021-12-27  

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