2010 Fiscal Year Final Research Report
Ascending spinal tract formation in developing chick
| Project/Area Number |
20200011
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Nerve anatomy/Neuropathology
Basic veterinary science/Basic zootechnical science
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
YAMAMOTO Tohru Hokkaido University, 大学院・薬学研究院, 准教授 (10251480)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | 脊髄上行路 / 脊髄小脳路 / 脊髄神経 / 神経回路網形成 |
|---|
| Research Abstract |
Ascending spinal tracts (AST) relay various external and internal information received in a body to the brain. The origins and destinations of AST have been extensively studied in wide variety of species ; however, relatively little is known on the pathways and processes taken by the axons to reach their destinations during development. We developed the method utilizing newly developed in ovo electroporation conditions for making possible to follow the single axons derived from an intended single spinal segment of chick embryos, and followed the elongation time course and the paths of the ascending axons, including the mammalian counterparts of ventral and dorsal spinocerebellar tracts. Our observations unveiled the pathways and elongation processes taken by AST neurons, and suggested that a spinal cord may provide cues to coordinate their behavior.
|
-
-
-
[Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.2010
Author(s)
Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, Taru H, Hata S, Yamamoto T , Saito Y, Suzuki T.
-
Journal Title
Mol. Neurodegener. 5
Pages: 35
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
