2010 Fiscal Year Final Research Report
Kidney regeneration using autologous stem cells
| Project/Area Number |
20200018
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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| Allocation Type | Single-year Grants |
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| Research Field |
Kidney internal medicine
Biomedical engineering/Biological material science
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
YOKOO Takashi Jikei University School of Medicine, 医学部, 講師 (70301538)
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| Co-Investigator(Kenkyū-buntansha) |
UECHI Masami 日本大学, 生物資源科学部, 准教授 (90296426)
OONISHI Akira 独立行政法人農業生物資源研究所, 遺伝子組換え家畜センター, 副研究主幹 (30414890)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 間葉系幹細胞 / 腎臓再生 / 異種胎仔 |
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| Research Abstract |
Significant advances have been made in stem cell research over the past decade. A number of non-hematopoietic sources of stem cells (or progenitor cells) have been identified including endothelial stem cells and neural stem cells. These discoveries have been a major step towards the potential regeneration of organs for clinical applications using stem cells. The worldwide shortage of donor kidneys means that this approach has garnered significant attention in the field of nephrology. We challenged to use autologous stem cells to build kidney using developmental program of xeno-embryo.
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[Presentation] Use of the E2F1 transgenic suicide-inducible mice permit regeneration of completely human kidneys.2010
Author(s)
Matsumoto K, Yokoo T, Yokote S, Kawamura T, Ohashi T, Hosoya T, Tsuji O, Okano JH, Okano H, Kobayashi E.
Organizer
American Society of Nephrology Renal Week
Place of Presentation
Denver CO, USA
Year and Date
2010-11-18
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