2010 Fiscal Year Final Research Report
Measurement and Numerical Modeling of the Characteristics of Red Blood Cell Suspended in Fluid Under Uniform Magnetic Field
| Project/Area Number |
20200026
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| Research Category |
Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thermal engineering
Microdevices/Nanodevices
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| Research Institution | Kyoto University |
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Principal Investigator |
TATSUMI Kazuya Kyoto University, 大学院・工学研究科, 准教授 (90372854)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 赤血球 / マイクロ流路 / 強磁場 / 数値解析 / 計算モデル / マイクロ電気センサ |
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| Research Abstract |
Experimental technology that can measure the magnetic and electric characteristics of a single red blood cell (RBC) suspended in a fluid exposed under strong magnetic field using high-speed camera, microchannels, micro-electric sensors was developed in this study. Further, a novel fluid temperature measurement in microchannels using fluorescent polarization method was also developed. By using these measurement technologies, the RBC motions in fluids under magnetic field of 0-10 Tesla could be analyzed. The measurement data was further used to develop a numerical model that can directly simulate the physics of the magnetic effect on the RBC membrane. This model possesses a high general versatility to simulate three-dimensional RBC motion in fluids and can be applied to a biologic numerical simulator.
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