2012 Fiscal Year Final Research Report
BioCMOS technology and its application to portable biosensor instruments
| Project/Area Number |
20226009
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| Research Category |
Grant-in-Aid for Scientific Research (S)
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| Allocation Type | Single-year Grants |
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| Research Field |
Electron device/Electronic equipment
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
UNO Shigeyasu 立命館大学, 理工学部, 准教授 (40420369)
OZAWA Hiroaki 中央大学, 理工学部, 助教 (50464152)
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| Project Period (FY) |
2008 – 2012
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| Keywords | 電子デバイス / 集積回路 |
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| Research Abstract |
BioCMOS technology, integration of biomolecules on semiconductor integrated circuit, has been developed, including new electrical detection methods of biomolecules, new design of analog CMOS integrated circuit, and new assembling technology . The target is portable gene-based point-of-care testing (POCT) system. Redox potential detection method has been developed and the signal stability was drastically improved by two orders. Fabricating a redox potential sensor array, accurately determination ofglucose levels in human blood and DNA sequencing were demonstrated. A multimodal electrochemical sensor arrays based on the detection of electric potential, current, and impedance, which enables synthetic analysis and makes it possible to standardize biosensor chip, has been developed.
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