2010 Fiscal Year Final Research Report
Novel Chemical Sensing Molecular Reagents for Bioimaging in living Cells and Organs
| Project/Area Number |
20245019
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Keio University |
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Principal Investigator |
SUZUKI Koji 慶應義塾大学, 理工学部, 教授 (80154540)
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| Co-Investigator(Kenkyū-buntansha) |
NIWA Osamu 独立行政法人産業技術総合研究所, 生物機能工学研究部門, 副部門長 (70392644)
HISAMOTO Hideaki 大阪府立大学, 大学院・工学研究科, 教授 (00286642)
CITTERIO Daniel 慶應義塾大学, 理工学部, 准教授 (00458952)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 蛍光プローブ / ケミカルバイオロジーツール / 化学発光分子 / 分子イメージング / MRIプローブ |
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| Research Abstract |
Several new types of revolutionary fluorescent probes have been developed, in order to satisfy the increasing demands and interest in biological substance imaging, as well as for the development of fluorescence imaging technology. However, unique chemical sensing probes, which are required for one of the cutting-edge topics in bioimaging, have not been well established. In this study, several new types of fluorescent/luminescent probes, redox probes and nuclear magnetic resonance probes (MRI probes), which have unique properties, were designed and synthesized for their application to bioimaging of substances in living cells and organs.
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