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2010 Fiscal Year Annual Research Report

サブナノ秒パルスパワー技術開発と環境・バイオ・リサイクル・微細加工・医療への応用

Research Project

Project/Area Number 20246053
Research InstitutionKumamoto University

Principal Investigator

秋山 秀典  熊本大学, 大学院・自然科学研究科, 教授 (50126827)

Co-Investigator(Kenkyū-buntansha) 勝木 淳  熊本大学, バイオエレクトリクス研究センター, 教授 (80233758)
浪平 隆男  熊本大学, バイオエレクトリクス研究センター, 准教授 (40315289)
佐久川 貴志  熊本大学, 大学院・自然科学研究科, 准教授 (40398186)
Keywords電気機器工学 / 電力工学 / プラズマ・核融合 / 環境
Research Abstract

パルス幅が数十ナノ秒の高繰り返しパルスパワー発生装置の開発と、環境浄化、バイオ技術、リサイクル、超微細加工などへの応用をこれまで行ってきた。本研究目的は、パルス幅を更に減少させて、サブナノ秒以下と極短パルスにした高繰り返しサブナノ秒パルスパワー発生装置の開発、サブナノ秒パルスパワーを高気圧気体、液体、超臨界流体及び固体に作用させて放電プラズマ生成、及び放電プラズマ或いはパルスパワーのバイオ・生体・化学物質等との相互作用を調べ、サブナノ秒パルスパワー応用としての新しい産業分野を形成する。さらに、パルスパワーのバイオへの作用とその環境・医療への応用という新しい分野であるバイオエレクトリクスの学問創生に寄与する。本年度は下記のような研究成果が得られた。1.サブナノ秒パルスパワーをヒラ細胞(人間の子宮がん細胞)に照射して、共焦点顕微鏡で15分ごと7日間形態変化を観測すると共に、フローサイトメーターを用いて、アポトーシスが起こっていることを確認した。さらに、楕円体ミラーによってパルスパワーを集束し、がん細胞への影響を調べ、有意差を確認した。2.万能細胞と言われているES細胞に、パルスパワーを印加して、細胞分化への影響を調べ、新しい作用因子となることを明らかにした。最初に、ES細胞の死滅が起こる電界強度と印加回数を調べた後、細胞分化への影響を調べた。更なる実験が必要ではあるが、細胞分化への影響が認められた。3.超臨界流体中放電プラズマ現象を、レーザ干渉計を用いて観測し、放電プラズマの進展状況や衝撃波の発生について明らかにした。

  • Research Products

    (64 results)

All 2011 2010

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (52 results)

  • [Journal Article] Anew application of underwater pulsed streamer-like discharge to transcriptional activation of retrotransposon of Porphyra yezoensis2010

    • Author(s)
      Douyan Wang, 他
    • Journal Title

      IEEE Transactions on Plasma Science

      Volume: 38 Pages: 39-46

    • Peer Reviewed
  • [Journal Article] Development of higher yield ozonizer based on nano-seconds pulsed discharge2010

    • Author(s)
      D.Wang, 他
    • Journal Title

      Journal of Advanced Oxidation Technologies

      Volume: 13 Pages: 71-78

    • Peer Reviewed
  • [Journal Article] Experimental study of toroidal shock wave focusing in a compact vertical annular diaphragmless shock tube2010

    • Author(s)
      S.H.R.Hosseini, 他
    • Journal Title

      Shock Waves

      Volume: 20 Pages: 1-7

    • Peer Reviewed
  • [Journal Article] High-Performance Pulsed Power Generator Controlled by FPGA2010

    • Author(s)
      Masahiro Akiyama, 他
    • Journal Title

      IEEE Transaction on Plasma Science

      Volume: 38 Pages: 2588-2592

    • Peer Reviewed
  • [Journal Article] Energy efficiency improvement of nitric oxide treatment using nano-seconds pulsed discharge2010

    • Author(s)
      T.Matsumoto, 他
    • Journal Title

      IEEE Transactions on Plasma Science

      Volume: 38 Pages: 2639-2643

    • Peer Reviewed
  • [Journal Article] Pulsed discharge induced by nano-seconds pulsed power in atmospheric air2010

    • Author(s)
      D.Wang, 他
    • Journal Title

      IEEE Transactions on Plasma Science

      Volume: 38 Pages: 2746-2751

    • Peer Reviewed
  • [Journal Article] Non-thermal and transient thermal effects of burst 100 MHz sinusoidal electric fields on apoptotic activity in HeLa cells2010

    • Author(s)
      Katsuki, S, 他
    • Journal Title

      IEEE Transactions on Dielectrics and Electrical Insulation

      Volume: 17 Pages: 678-684

    • Peer Reviewed
  • [Journal Article] 水中ストリーマ状放電プラズマ生成のための高繰り返し小型磁気パルス圧縮回路開発2010

    • Author(s)
      上野崇寿, 他
    • Journal Title

      電気学会論文誌A,基礎・材料・共通部門(IEEJ Transactions on Fundamentals and Materials)

      Volume: 130 Pages: 567-572

    • Peer Reviewed
  • [Journal Article] パルスパワー方式高発生量コンパクトオゾナイザの開発2010

    • Author(s)
      田中文章, 他
    • Journal Title

      電気学会論文誌A,基礎・材料・共通部門(IEEJ Transactions on Fundamentals and Materials)

      Volume: 130 Pages: 579-583

    • Peer Reviewed
  • [Journal Article] 超臨界流体の誘電・放電・プラズマ特性2010

    • Author(s)
      喜屋武毅, 他
    • Journal Title

      プラズマ・核融合学会誌

      Volume: 86 Pages: 317-323

    • Peer Reviewed
  • [Journal Article] Xenon Discharge-Produced Plasma Radiation Source for EUV Lithography2010

    • Author(s)
      C.H, Zhang, 他
    • Journal Title

      IEEE Industry Applications Society

      Volume: 46 Pages: 1661-1666

    • Peer Reviewed
  • [Journal Article] High-Performance Pulsed-Power Generator Controlled by FPGA2010

    • Author(s)
      M.Akiyama, 他
    • Journal Title

      IEEE Transactions on Plasma Science

      Volume: 38 Pages: 2588-2592

    • Peer Reviewed
  • [Presentation] Flexible Control of Pulsed Power Using Embedded System and PC2011

    • Author(s)
      秋山雅裕, 他
    • Organizer
      ISPIasma2011
    • Place of Presentation
      名古屋工業大学(愛知県)
    • Year and Date
      2011-03-08
  • [Presentation] Higher Yield Ozone Generation Using Nano-Seconds Pulsed Discharge2011

    • Author(s)
      浪平隆男
    • Organizer
      18th Symposium on Application of Plasma Processes Workshop on Plasmas as a Planetary Atmosphere Mimics
    • Place of Presentation
      Hotel Boboty, Vratna, Mala Fatra, Slovakia
    • Year and Date
      2011-01-19
  • [Presentation] nsパルス放電を用いた省エネ型オゾン生成システムの高濃度・大容量化へ向けた取り組み2010

    • Author(s)
      松本宇生, 他
    • Organizer
      パルスパワー放電合同研究会
    • Place of Presentation
      長岡技術科学大学(新潟県)
    • Year and Date
      20101514
  • [Presentation] パソコンとFPGAを用いたパルスパワー制御2010

    • Author(s)
      秋山雅裕, 他
    • Organizer
      研究会「パルスパワー技術を基礎とするプラズマの物理とその応用」
    • Place of Presentation
      核融合科学研究所(岐阜県)
    • Year and Date
      2010-12-22
  • [Presentation] 超臨界二酸化炭素中の放電プラズマ現象2010

    • Author(s)
      猪原武士, 他
    • Organizer
      研究会「パルスパワー技術を基礎とするプラズマの物理とその応用」
    • Place of Presentation
      核融合科学研究所(岐阜県)
    • Year and Date
      2010-12-21
  • [Presentation] バーストAC高電界による動物細胞の増殖活性変化2010

    • Author(s)
      矢野正彦, 他
    • Organizer
      電気学会プラズマパルスパワー 合同研究会
    • Place of Presentation
      東京工業大学(東京都)
    • Year and Date
      2010-12-17
  • [Presentation] ナノ秒パルス放電プラズマによる省エネルギー型気相化学反応炉の形成2010

    • Author(s)
      松本宇生, 他
    • Organizer
      電気学会プラズマパルスパワー 合同研究会
    • Place of Presentation
      東京工業大学(東京都)
    • Year and Date
      2010-12-17
  • [Presentation] PCRを用いたパルス高電界による細胞死のメカニズム解析2010

    • Author(s)
      光武和典, 他
    • Organizer
      電気学会プラズマパルスパワー 合同研究会
    • Place of Presentation
      東京工業大学(東京都)
    • Year and Date
      2010-12-17
  • [Presentation] 同軸構造磁気パルス圧縮回路によるパルスパワー電源の短パルス化2010

    • Author(s)
      上田悟, 他
    • Organizer
      プラズマ パルスパワー 合同研究会
    • Place of Presentation
      東京工業大学(東京都)
    • Year and Date
      2010-12-16
  • [Presentation] 高圧・高密度媒体中でのレーザー生成プラズマの特性とその応用2010

    • Author(s)
      浪平隆男, 他
    • Organizer
      プラズマ・核融合学会 第27回年会
    • Place of Presentation
      北海道大学学術交流会館(北海道)
    • Year and Date
      2010-12-03
  • [Presentation] Response of Mammalian Cells to Pulsed Electric Fields2010

    • Author(s)
      勝木淳
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea(招待講演)
    • Year and Date
      2010-10-14
  • [Presentation] BIOMEDICAL APPLICATION OF NANOSECOND ELECTRIC PULSE GENERATED UNDERWATER SHOCK WAVES2010

    • Author(s)
      S.H.R.Hosseini, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-14
  • [Presentation] PERFORMANCES OF 2 NS PULSED DISCHARGE PLASMA2010

    • Author(s)
      松本宇生, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-14
  • [Presentation] ENERGY TRANSFER EFFICIENCY OF NANO-SECONDS PULSED POWER GENERATOR FOR NON-THERMAL PLASMA PROCESSING2010

    • Author(s)
      松田樹也, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-14
  • [Presentation] FLEXIBLE CONTROL OF PULSED POWER USING FPGA AND PC2010

    • Author(s)
      秋山秀典, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] REPETITIVE COMPACT PULSED POWER GENERATOR USING IGBTS AND PULSE COMPRESSION CIRCUIT2010

    • Author(s)
      佐久川貴志, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] MEASUREMENT OF ELECTRON ENERGY DURING PULSED DISCHARGE IN ATMOSPHERIC GAS2010

    • Author(s)
      岡田翔, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] INTRODUCTION OF RECYCLED AGGREGATE PRODUCTION SYSTEM BASED ON PULSED DISCHARGE INSIDE OF WASTE CONCRETE2010

    • Author(s)
      緒方恵介, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] PHYSICAL PARAMETERS OF LASER-PRODUCED PLASMA INHIGH PRESSURE FLUID2010

    • Author(s)
      高武和英, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] IMPROVEMENT OF ENERGY TRANSFER EFFICIENCY DURINGOZONE PRODUCTION USING NANO-SECONDS PULSED DISCHARGE2010

    • Author(s)
      荒木良孝, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] INFLUENCE OF FEEDING GAS HUMIDITY IN NANOSECONDS PULSED DISCHARGE BASED OZONIZER2010

    • Author(s)
      廣田智行, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] INFLUENCE OF GAS COMPOSITIONS ON NO REMOVAL USING NANO-SECONDS PULSED DISCHARGE2010

    • Author(s)
      島崎祐輔, 他
    • Organizer
      EAPPC2010/BEAMS2010
    • Place of Presentation
      Jeju International Convention Center, Jeju, Korea
    • Year and Date
      2010-10-12
  • [Presentation] Efficient non-thermal plasma processing by 5 nspulsed discharge2010

    • Author(s)
      浪平隆男, 他
    • Organizer
      63rd Annual Gaseous Electronics Conference and 7th International Conference on Reactive Plasmas
    • Place of Presentation
      The Maison dela Chimie, Paris, France
    • Year and Date
      2010-10-05
  • [Presentation] Shadowgraph Visualizations of Pulsed Discharge Phenomena in Pressurized Carbon Dioxide up to Supercritical Conditions2010

    • Author(s)
      喜屋武毅, 他
    • Organizer
      63rd Annual Gaseous Electronics Conference and 7th International Conference on Reactive Plasmas
    • Place of Presentation
      Maison dela Chimie, Paris, France
    • Year and Date
      2010-10-05
  • [Presentation] Flexible Control of Pulsed Power for Biomedical Applications using PC2010

    • Author(s)
      松本宇生, 他
    • Organizer
      63rd Annual Gaseous Electronics Conference and 7th International Conference on Reactive Plasmas
    • Place of Presentation
      Maison dela Chimie, Paris, France
    • Year and Date
      2010-10-05
  • [Presentation] Measurement of Spatiotemporal Gas Temperature during Pulsed Discharge2010

    • Author(s)
      岡田翔, 他
    • Organizer
      63rd Annual Gaseous Electronics Conference and 7th International Conference on Reactive Plasmas
    • Place of Presentation
      Maison dela Chimie, Paris, France
    • Year and Date
      2010-10-05
  • [Presentation] バーストAC高電界による対する動物細胞の応答解析2010

    • Author(s)
      松本千春, 他
    • Organizer
      平成22年度(第63回)電気関係学会九州支部連合大会
    • Place of Presentation
      九州産業大学(福岡県)
    • Year and Date
      2010-09-25
  • [Presentation] ナノ秒パルス高電界印加時のHelaS3細胞におけるmRNAの発言に関する研究2010

    • Author(s)
      矢野美沙子, 他
    • Organizer
      平成22年度(第63回)電気関係学会九州支部連合大会
    • Place of Presentation
      九州産業大学(福岡県)
    • Year and Date
      2010-09-25
  • [Presentation] 超臨界二酸化炭素におけるナノ秒パルスストリーマーの観測2010

    • Author(s)
      猪原武士, 他
    • Organizer
      平成22年電気学会基礎・材料・共通部門大会
    • Place of Presentation
      琉球大学(沖縄県)
    • Year and Date
      2010-09-13
  • [Presentation] Phenomena of Discharge Plasmas in Water Produced by High Repetitive Pulsed Power Generator2010

    • Author(s)
      秋山秀典
    • Organizer
      4th Japan/US Symposium On Pulsed Power And Plasma Applications
    • Place of Presentation
      Sheraton Princess Kaiulani Hotel, Honolulu, Hawaii, USA
    • Year and Date
      2010-08-05
  • [Presentation] Biological Response of HeLa Cells to the Application of Non-thermal Burst AC Fields2010

    • Author(s)
      勝木淳
    • Organizer
      4th Japan/US Symposium On Pulsed Power And Plasma Applications
    • Place of Presentation
      Sheraton Princess Kaiulani Hotel, Honolulu, Hawaii, USA
    • Year and Date
      2010-08-05
  • [Presentation] Process of Pulsed Electrical Breakdown in High-Pressure Carbon Dioxide Including Supercritical Phase2010

    • Author(s)
      喜屋武毅, 他
    • Organizer
      4th Japan/US Symposium On Pulsed Power And Plasma Applications
    • Place of Presentation
      Sheraton Princess Kaiulani Hotel, Honolulu, Hawaii, USA
    • Year and Date
      2010-08-05
  • [Presentation] Voltage Control of Pulsed Power using FPGA2010

    • Author(s)
      秋山雅裕
    • Organizer
      4th Japan/US Symposium On Pulsed Power And Plasma Applications
    • Place of Presentation
      Sheraton Princess Kaiulani Hotel, Honolulu, Hawaii, USA
    • Year and Date
      2010-08-05
  • [Presentation] Effect of pulsing sequence of nanosecond pulsed electric fields on HeLa S3 cells and mature fat cells2010

    • Author(s)
      安部恵祐, 他
    • Organizer
      7th International Bioelectrics Symposium
    • Place of Presentation
      Old Dominion University, Norfolk, VA, USA
    • Year and Date
      2010-06-26
  • [Presentation] Response of HeLa cells to narrow band intense pulsed electric fields2010

    • Author(s)
      勝木淳
    • Organizer
      7th International Bioelectrics Symposium
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-25
  • [Presentation] Identification of the intracellular signaling pathway that is activated by nanosecond pulsed electric fields in human cells2010

    • Author(s)
      矢野憲一
    • Organizer
      7th International Bioelectrics Symposium
    • Place of Presentation
      Old Dominion University, Norfolk, VA, USA
    • Year and Date
      2010-06-25
  • [Presentation] Compact therapeutic shock wave generators using magnetic pulse compression circuits2010

    • Author(s)
      S.H.R.Hosseini
    • Organizer
      7th International Bioelectrics Symposium
    • Place of Presentation
      Old Dominion University, Norfolk, VA, USA
    • Year and Date
      2010-06-25
  • [Presentation] Different discharge phenomena between general and nano-seconds pulsed discharges2010

    • Author(s)
      浪平隆男, 他
    • Organizer
      International Symposium on Non-Thermal/Thermal Plasma Pollution Control Technology and Sustainable Energy (ISNTPT-7)
    • Place of Presentation
      St.John's Newfoundland, Canada
    • Year and Date
      2010-06-25
  • [Presentation] Medical and Environmental Applications in the field of Bioelectrics2010

    • Author(s)
      秋山秀典
    • Organizer
      7th International Bioelectrics Symposium
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA(招待講演)
    • Year and Date
      2010-06-24
  • [Presentation] Study of mRNA expression in HeLa cells subjected to intense pulsed electric fields2010

    • Author(s)
      壇達也, 他
    • Organizer
      7th International Bioelectrics Symposium
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-24
  • [Presentation] EXPERIMENTAL STUDY OF CONVERGING SPHERICAL SHOCK WAVE DRIVEN RICHTMYER-MESHKOV INSTABILITY2010

    • Author(s)
      S.H.R.Hosseini, 他
    • Organizer
      the 37th IEEE International Conference on Plasma Science
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-21
  • [Presentation] HIGH SPEED VISUALIZATION OF THE EFFECTS OF OUTPUT PEAKING CAPACITOR ON UNDERWATER STREAMER PROPAGATION2010

    • Author(s)
      S.H.R.Hosseini, 他
    • Organizer
      the 37th IEEE International Conference on Plasma Science
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-21
  • [Presentation] EFFECT OF PULSING SEQUENCE OF NANOSECONDPULSED ELECTRICS FIELDS ON HELA CELLS2010

    • Author(s)
      安部恵祐, 他
    • Organizer
      the 37th IEEE International Conference on Plasma Science
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-21
  • [Presentation] STUDY OF PROTEIN ACTIVITY IN HELA CELLS SUBJECTED TO NANOSECOND PULSED ELECTRIC FIELDS2010

    • Author(s)
      壇達也, 他
    • Organizer
      the 37th IEEE International Conference on Plasma Science
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-21
  • [Presentation] MAMMALIAN CELL RESPONSE TO THE APPLICATION OF INTENSE BURST SINUSOIDAL ELECTRIC FIELDS2010

    • Author(s)
      矢野正彦, 他
    • Organizer
      the 37th IEEE International Conference on Plasma Science
    • Place of Presentation
      Marriott Waterside hotel, Norfolk, VA, USA
    • Year and Date
      2010-06-21
  • [Presentation] RESPONSE OF MAMMALIAN CELLS SUBJECTED TO INTENSE BURST SINUSOIDAL ELECTRIC FIELDS2010

    • Author(s)
      矢野正彦, 他
    • Organizer
      2010 International Power Modulator and High Voltage Conference
    • Place of Presentation
      The Westin Peachtree Plaza, Atlanta, GA, USA
    • Year and Date
      2010-05-26
  • [Presentation] EFFECT OF PULSING SEQUENCE OF NANOSECOND PULSED ELECTRIC FIELDS ON HELA CELLS2010

    • Author(s)
      光武和典, 他
    • Organizer
      2010 International Power Modulator and High Voltage Conference
    • Place of Presentation
      The Westin Peachtree Plaza, Atlanta, GA, USA
    • Year and Date
      2010-05-26
  • [Presentation] EMBRYONIC DEVELOPMENT OF MEDAKA FISH EGG AFTER NANOSECOND PULSED ELECTRIC FIELD APPLICATION2010

    • Author(s)
      姜東求, 他
    • Organizer
      2010 International Power Modulator and High Voltage Conference
    • Place of Presentation
      The Westin Peachtree Plaza, Atlanta, GA, USA
    • Year and Date
      2010-05-26
  • [Presentation] OBSERVATION OF PULSED DISCHARGE PHENOMENA IN SUPERCRITICAL CARBON DIOXIDE BY MEANS OF LASER INTERFEROMETRY2010

    • Author(s)
      猪原武士, 他
    • Organizer
      2010 International Power Modulator and High Voltage Conference
    • Place of Presentation
      The Westin Peachtree Plaza, Atlanta, GA, USA
    • Year and Date
      2010-05-26
  • [Presentation] Medical, Biological and Environmental Applications of High Performance Pulsed Power2010

    • Author(s)
      秋山秀典
    • Organizer
      2010 International Power Modulator and High Voltage Conference
    • Place of Presentation
      The Westin Peachtree Plaza Hotel, Atlanta, GA, USA(招待講演)
    • Year and Date
      2010-05-25
  • [Presentation] 圧力制御液体下におけるレーザー生成化学反応場の創生2010

    • Author(s)
      浪平隆男
    • Organizer
      パルスパワー放電合同研究会
    • Place of Presentation
      長岡技術科学大学(新潟県)
    • Year and Date
      2010-05-15
  • [Presentation] バーストAC高電界に対する動物細胞の反応解析2010

    • Author(s)
      勝木淳, 他
    • Organizer
      パルスパワー放電合同研究会
    • Place of Presentation
      長岡技術科学大学(新潟県)
    • Year and Date
      2010-05-14

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Published: 2012-07-19  

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