2010 Fiscal Year Final Research Report
Molecular combination dial and nano-cage
| Project/Area Number |
20300106
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | The University of Tokyo |
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Principal Investigator |
HAGIYA Masami The University of Tokyo, 大学院・情報理工学系研究科, 教授 (30156252)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Fumiaki 東京大学, 大学院・情報理工学系研究科, 助教 (50456159)
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| Research Collaborator |
HIRABAYASHI Miki 情報通信研究機構, 研究員
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| Project Period (FY) |
2008 – 2010
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| Keywords | DNA計算 / DNAナノテク / 三次元ナノ構造 / 分子システム / AFM測定 |
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| Research Abstract |
We developed a "molecular combination dial," which can be controlled by the order of multiple inputs, and a "nano-cage," which can be combined with the dial.
In detail, we successfully constructed DNA capsules that can be broken by UV light (nano-cage) by inserting a photo-controllable molecule (azobenzene) into DNA buckyballs developed by Mao. Moreover, we developed a molecular machine that can be controlled by the order of UV light irradiation and addition of ATP (molecular combination dial), with the use of a computer program for automatic design.
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