2010 Fiscal Year Final Research Report
Development of On-Chip Cell Manipulation System Capable of Massively Parallel Patterning of Single Cells
| Project/Area Number |
20300156
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Toyohashi University of Technology |
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Principal Investigator |
SHIBATA Takayuki Toyohashi University of Technology, 大学院・工学研究科, 教授 (10235575)
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| Co-Investigator(Renkei-kenkyūsha) |
KISHIDA Akio 東京医科歯科大学, 生体材料工学研究所, 教授 (60224929)
KAWASHIMA Takahiro 豊橋技術科学大学, 大学院・工学研究科, 助教 (50378270)
NAGAI Moeto 豊橋技術科学大学, 大学院・工学研究科, 助教 (00580557)
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| Project Period (FY) |
2008 – 2010
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| Keywords | マイクロマニピュレータアレイ / セルパターニング / 細胞操作 / 細胞機能解析 / マイクロニードル / MEMS / ナノバイオテクロノジー |
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| Research Abstract |
A good understanding of extensive cellular knowledge is a prerequisite to enabling innovative technological advances in the field of highly-advanced medical treatment and drug discovery, because biological cells are the structural and functional units of all known living organisms. Cell patterning that enables in vitro patterned cell culture is one of the key technologies for addressing fundamental issues related to single cell analysis and cellular network analysis. Therefore, this research focused on the development of a novel cell patterning technique based on a micromanipulator array integrated with microvalves capable of massively parallel trapping and manipulation of single living cells.
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