2011 Fiscal Year Final Research Report
Establishing clinical evidence for prevention of lifestyle-related disease and lifestyle intervention
Project/Area Number |
20300227
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Applied health science
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Research Institution | University of Tsukuba (2009-2011) Ochanomizu University (2008) |
Principal Investigator |
SONE Hirohito 筑波大学, 医学医療系, 教授 (30312846)
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Co-Investigator(Renkei-kenkyūsha) |
YAMADA Nobuhiro 筑波大学, 学長 (40200729)
OHASHI Yasuo 東京大学, 大学院・医学系研究科, 教授 (00134461)
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Project Period (FY) |
2008 – 2011
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Keywords | 生活習慣病・科学的エビデンス / 健康寿命 / 生活習慣改善 |
Research Abstract |
To investigate effects and significance of lifestyles and their modification on management and prevention of life-style related diseases such as type 2 diabetes or metabolic syndrome, we integrated various related scientific fields involving medicine, nutritional and exercise sciences, statistics and established enormous number of clinical evidences including 54 original articles in international quality journals.
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Research Products
(79 results)
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[Journal Article] Low BMI at age 20 years predicts gestational diabetes independent of BMI in early pregnancy : Tanaka Women's Clinic Study2012
Author(s)
Yachi Y, Tanaka Y, Nishibata I, Horikawa C, Hei anza Y, Sugawara A, Saito A, Yasuhara M, Koba yashi K, Kodama S, Saito K, Sone H
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Journal Title
Diabet Med
Volume: (in press)
Peer Reviewed
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[Journal Article] Longitudinal trajectories of HbA1c and fasting plasma glucose levels during the development of type 2 diabetes : TOPICS 72012
Author(s)
Heianza Y, Arase Y, Fujihara K, Hsieh SD, SaitoK, Tsuji H, Kodama S, Yahagi N, Shimano H, Yamada N, Hara S, Sone H
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Journal Title
Diabetes Care
Volume: (in press)
DOI
Peer Reviewed
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[Journal Article] on behalf of Japan Diabetes Clinical Data Management Study Group. Chronic kidney disease categories and renalcardiovascular outcomes in type 2 diabetes without prevalent cardiovascular disease : a pro-spective cohort study2012
Author(s)
Yokoyama H, Araki S, Haneda M, Matsushima M, Kawai K, Hirao K, Oishi M, Sugimoto K, Sone H, Maegawa H, Kashiwagi A
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Journal Title
Diabetologia
Volume: (in press)
Peer Reviewed
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[Journal Article] High normal HbA1c levels were associated with impaired insulin secretion without escalating insulin resistance in Japanese individuals : The Toranomon Hospital Health Management Center Study 8 (TOPICS 8)2012
Author(s)
Heianza Y, Arase Y, Fujihara K, Tsuji H, Saito H, Hsieh SD, Kodama S, Shimano1 H, Yamada N, Hara S, Sone H
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Journal Title
Diabet Med
Volume: (in press)
Peer Reviewed
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[Journal Article] Effect of Web-based Lifestyle Modification on Weight Control : A Meta-analysis2012
Author(s)
Kodama S, Saito K, Tanaka S, Horikawa C, Fujiwara K, Hirasawa R, Yachi Y, Iida KT, Shimano H, Ohashi Y, Yamada N, Sone H
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Journal Title
Int J Obes
Volume: (in press)
Peer Reviewed
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[Journal Article] Comparison of Various Lipid Variables as Predictors of Coronary Heart Disease in Japanese Men and Women with Type 2 Diabetes. Subanalysis of the Japan Diabetes Complications Study (JDCS)2012
Author(s)
Sone H, Tanaka S, Tanaka S, Iimuro S, Ishibashi S, Oikawa S, Shimano H, Katayama S, Ohashi Y, Akanuma Y, Yamada N
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Journal Title
Diabetes Care
Volume: (in press)
DOI
Peer Reviewed
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[Journal Article] the Japanese Elderly Intervention Trial Research Group. Non-high-density lipoprotein cholesterol : An important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients2012
Author(s)
Araki A, Iimuro S, Sakurai T, Umegaki H, Iijima K, Nakano H, Oba K, Yokono K, Sone H, Yamada N, Ako J, Kozaki K, Miura H, Kashiwagi A, Kikkawa R, Yoshimura Y, NakanoT, Ohashi Y, Ito H
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Journal Title
Geriatr Gerontol Int
Volume: 12
Pages: 18-28
Peer Reviewed
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[Journal Article] Background to Discuss Guidelines for Control of Plasma HDL Cholesterol in Japan2012
Author(s)
Yokoyama S, Yamashita S, Ishibashi S, Sone H, Oikawa S, Shirai K, Ohta T, Bujo H, Kobayashi J, Arai H, Harada-Shiba M, Eto M, Hayashi T, Gotoda T, Suzuki H, Yamada N
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Journal Title
J Atheroscler Thromb
Volume: 19
DOI
Peer Reviewed
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[Journal Article] Management of Type IIb Dyslipidemia2012
Author(s)
Arai H, Ishibashi S, Bujo H, Hayashi T, Yokoyama S, Oikawa S, Kobayashi J, Shirai K, Ota T, Yamashita S, Gotoda T, Harada-Shiba M, Sone H, Eto M, Suzuki H, Yamada N.
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Journal Title
J Atheroscler Thromb
Volume: 19
Pages: 105-14
DOI
Peer Reviewed
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[Journal Article] Impact of introducing HbA1c into the diagnostic criteria on prevalence and cardiovascular risk profiles of individuals with newly diagnosed diabetes in Japan : The Toranomon Hospital Health Management Center Study 2 (TOPICS 2)2012
Author(s)
Heianza Y, Hara S, Arase Y, Saito K, Tsuji H, Kodama S, Hsieh SD, Mori Y, Okubo M, Yamada N, Kosaka K, Sone H
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Journal Title
Diabet Res Clin Prac
Volume: 95
Pages: 283-290
DOI
Peer Reviewed
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[Journal Article] Research Committee for Primary Hyperlipidemia, Research on Measures against Intractable Diseases by the Ministry of Health, Labour and Welfare in Japan. Diagnosis and management of type I and type V hyperlipoproteinemia2012
Author(s)
Gotoda T, Shirai K, Ohta T, Kobayashi J, Yokoyama S, Oikawa S, Bujo H, Ishibashi S, Arai H, Ya mashita S, Harada-Shiba M, Eto M, Hayashi T, Sone H, Suzuki H, Yamada N
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Journal Title
J Atheroscler Thromb
Volume: 19
Pages: 1-12
DOI
Peer Reviewed
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[Journal Article] Factors associated with inappropriate weight loss attempts by early adolescent girls in Japan2011
Author(s)
Sugawara A, Sato M, Totsuka K, Saito K, Kodama S, Fukushi A, Yamanashi Y, MatsushimaE, Fujiwara Y, Suzuk E, Kondo K, Yamamoto Y, Sone H
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Journal Title
Eat Weight Dis
Volume: 16
Pages: e157-e163
Peer Reviewed
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[Journal Article] Serum Level of Triglycerides is a Potent Risk Factor Comparable to LDL Cholesterol for Coronary Heart Disease in Japanese Patients with Type 2 Diabetes. Subanalysis of the Japan Diabetes Complications Study (JDCS)2011
Author(s)
Sone H, Tanaka S, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Ohashi Y, Akanuma Y, Yamada N
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Journal Title
J Clin Endocrinol Metab
Volume: 96
Pages: 3448-56
DOI
Peer Reviewed
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[Journal Article] Self-reported fast eating is a potent predictor of development of impaired glucose tolerance in Japanese men and women : Tsukuba Medical Center Study2011
Author(s)
Totsuka K, Maeno T, Saito K, Kodama S, Asumi M, Yachi Y, Hiranuma Y, Shimano H, Yamada N, Ono Y, Naito T, Sone H
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Journal Title
Diabet Res Clin Prac
Volume: 94
Pages: e72-e74
DOI
Peer Reviewed
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[Journal Article] insulin and blood glucose control status alter the risk of ischemic heart disease and stroke among elderly diabetic patients2011
Author(s)
Hayashi T, Kawashima S, Nomura H, Itoh H, Wa tanabe H, Ohrui T, Yokote K, Sone H, Hattori Y, Yoshizumi M, Ina K, Kubota K. Age, gender
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Journal Title
Cardiovasc Diabetol
Volume: 10
Pages: 86
DOI
Peer Reviewed
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[Journal Article] Quality of Internet information related to the Mediterranean diet2011
Author(s)
Hirasawa R, Saito K, Yachi Y, Ibe Y, Kodama S, Asumi M, Horikawa C, Saito A, Heianza Y, Sato K, Kondo K, Shimano H, Sone H
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Journal Title
Public Health Nutr
Volume: 19
Pages: 1-9
DOI
Peer Reviewed
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[Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011
Author(s)
Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa N, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N Shimano H
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Journal Title
Arterioscler Thromb Vasc Biol
Volume: 31
Pages: 1973-9
DOI
Peer Reviewed
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[Journal Article] HbA1c 5.7-6.4% and impaired fasting plasma glucose for diagnosis of prediabetes and risk of progeression to diabetes in Japan (TOPICS 3) : a longitudinal cohort study2011
Author(s)
Heianza Y, Hara S, Arase Y, Saito K, Fujiwara K, Tsuji H, Kodama S, Hsieh SD, Mori Y, Shimano H, Yamada N, Kosaka K, Sone H
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Journal Title
Lancet
Volume: 378
Pages: 147-55
DOI
Peer Reviewed
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[Journal Article] Low Serum Potassium Levels and Risk of Type 2 Diabetes : Toranomon Hospital Health Management Center Study 1 (TOPICS 1)2011
Author(s)
Heianza Y, Hara S, Arase Y, Saito K, Totsuka K, Tsuji H, Kodama S, Hsieh SD, Yamada N, Kosaka K, Sone H
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Journal Title
Diabetologia
Volume: 54
Pages: 762-766
DOI
Peer Reviewed
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[Journal Article] Alcohol Consumption and Risk of Atrial Fibrillation : A Meta-analysis2011
Author(s)
Kodama S, Saito K, Tanaka S, Horikawa C, Saito A, Heianza Y, Anasako Y, Nishigaki Y, Yachi Y, Iida KT, Ohashi Y, Yamada N, Sone H
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Journal Title
J Am Coll Cardiol
Volume: 57
Pages: 427-36
DOI
Peer Reviewed
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[Journal Article] Long-term lifestyle intervention lowers incidence of stroke in Japanese patients with type 2 diabetes : a nationwide multicenter randomised controlled trial. (the Japan Diabetes Complications Study)2010
Author(s)
Sone H, Tanaka S, Iimuro S, Tanaka S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Yamashita H, Ito H, Yoshimura Y, Ohashi Y, Akanuma Y, Yamada N
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Journal Title
Diabetologia
Volume: 53
Pages: 419-428
DOI
Peer Reviewed
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[Journal Article] Components of metabolic syndrome and their combinations as predictors of cardiovascular disease in Japanese patients with type 2 diabetes. Implications for improved definition. Analysis from Japan Diabetes Complications Study (JDCS)2009
Author(s)
Sone H, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Ito H, Ohashi Y, Akanuma Y, Yamada N
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Journal Title
J Atheroscler Thromb
Volume: 16
Pages: 380-387
DOI
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[Journal Article] Low HDL-cholesterol is associated with the risk of stroke in elderly diabetic individuals : Changes in the risk for atherosclerotic diseases at various ages2009
Author(s)
Hayashi T, Kawashima S, Itoh H, Yamada N, Sone H, Watanabe H, Hattori Y, Ohrui T, Yokote K, Nomura H, Umegaki H, Iguchi A
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Journal Title
Diabetes Care
Volume: 32
Pages: 1221-1223
DOI
Peer Reviewed
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[Journal Article] Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women2009
Author(s)
Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H
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Journal Title
JAMA
Volume: 301
Pages: 2024-2035
DOI
Peer Reviewed
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[Journal Article] Wais tcircumference as a cardiovascular and metabolic risk in Japanese patients with type 2 diabetes2009
Author(s)
Sone H, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Ishibashi S, Oikawa S, Katayama S, Ito H, Ohashi Y, Akanuma Y, Yamada N
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Journal Title
Obesity
Volume: 17
Pages: 585-92
DOI
Peer Reviewed
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[Journal Article] Influence of Fat and Carbohydrate Proportions on the Metabolic Profile in Patients with Type 2 Diabetes : A Meta-analysis2009
Author(s)
Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Sato M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H
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Journal Title
Diabetes Care
Volume: 32
Pages: 959-965
DOI
Peer Reviewed
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[Presentation] Potential impact of elevated HbA1c and impared fasting glucose on population for predicting risk of diabetes : The Toranomon Hospital Health Management Center Study2011
Author(s)
Heianza Y, Hara S, Horikawa C, Saito K, Suga wara A, Fujiwara K, Kodama S, Hsieh SD, Tsuji H, Shimano H, Yamada N, Arase Y, Sone H
Organizer
47th EASD Annual Meeting
Place of Presentation
Lisbon, Portugal
Year and Date
2011-09-13
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[Presentation] Diabetes and Risk of Hearing Impairment : A Meta-analysis2011
Author(s)
Horikawa C, Kodama S, Heianza Y, Saito A, Hirasawa R, Sugawara A, Totsuka K, Maki M, Saito K, Sone H
Organizer
71th American Diabetes Association (ADA) Scientific Sessions
Place of Presentation
San Diego, USA
Year and Date
2011-06-25
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[Presentation] HbA1c variability and risk of development of microalbuminuria in Japanese patients with type 2 diabetes : a pilot study, Tsukuba Kawai Diabetes Registry32011
Author(s)
Sugawara A, Kawai K, Motohashi S, Fujiwara K, Hirasawa R, Igawa K, Kobayashi K, Saito K, Ya mazaki K, Sone H
Organizer
71th ADA Scientific Sessions
Place of Presentation
San Diego, USA
Year and Date
2011-06-25
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[Presentation] Is the waist-to-statue ratio a better predictor than other anthropometric indicators to predict future diabetes risk? A meta-analysis2011
Author(s)
Kodama S, Horikawa C, Heianza Y, Sugawara A, Ibe Y, Yachi Y, Maki M, Shu M, Saito K, Sone H
Organizer
71th ADA Scientific Sessions
Place of Presentation
San Diego, USA
Year and Date
2011-06-25
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[Presentation] Japan Diabetes Complication Study Group. Dietary intake in Japanese patients with type 2 diabetes : Japan Diabetes Complication Study (JDCS)2011
Author(s)
Horikawa C, Yoshimura Y, Nishigaki Y, Tanaka S, Tanaka S, Kamada C, Okumura R, Ito H, Ohashi Y, Yamada N, Sone H
Organizer
71th ADA Scientific Sessions
Place of Presentation
San Diego, USA
Year and Date
2011-06-25
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[Presentation] Weight History as a screening tool for identifying undiagnosed deabetes and pre-diabetes in Japanese men (TOPICS)2011
Author(s)
Yoshizawa S, Heianza Y, Fujihara K, hara S, Saito K, Tsuji H, Kodama S, Arase Y, Yamada N, Kosa ka K, Sone H
Organizer
71th ADA Scientific Sessions
Place of Presentation
San Diego, USA
Year and Date
2011-06-25
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[Presentation] Simple Self-Report Questions on Behavioral or Psychological Symptoms Can Effectively Predict Future Type2 Diabetes (T2DM) : Toranomon Hospital Health Management Center Study (TOPICS)2010
Author(s)
Heianza Y, Nishigaki Y, Saito K, Totsuka K, Kodama S, Tsuji H, Hara S, Arase Y, Yamada N, Kosaka K, Sone H
Organizer
70^<th> ADA Scientific Sessions
Place of Presentation
Orlando, Florida
Year and Date
2010-06-27
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[Presentation] Comparison between Fasting and Post-Load Glucose Values as a Continuous Risk Factor for Cardiovascular Disease : A Meta-Analysis2010
Author(s)
Kodama S, Horikawa C, Anasako Y, Saito K, Hirasawa R, Ibe Y, Yachi Y, Asumi M, Shimano H, Yamada N, Sone H
Organizer
70^<th> ADA Scientific Sessions
Place of Presentation
Orlando, Florida
Year and Date
2010-06-27
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[Presentation] Association between sleep duration and diabetes control status among Japanese men and women with type 2 deabetes : The Japanese Diabetes Data Management (JDDM) Study2010
Author(s)
Saito A, Nishigaki Y, Yanagisawa M, Kawai K, Kuribayashi N, Yokoyama H, Sugimoto H, Oishi M, Wada T, Iwasaki K, Yagi N, Okuguchi F, Miyazawa K, Arai K, Saito K, Sone H
Organizer
70^<th>ADA Scientific Sessions
Place of Presentation
Orlando, Florida
Year and Date
2010-06-27
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