2010 Fiscal Year Final Research Report
Microelectrode Techniques for Cellular Engineering
| Project/Area Number |
20310070
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAJI Hirokazu 東北大学, 大学院・工学研究科, 准教授 (70431525)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 細胞チップ / 筋肉細胞 / 導電性高分子 |
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| Research Abstract |
We have succeeded in developing a technique to culture myotubes on a fibrin gel sheet. The prepared myotube culture on the hydrogel stably contract on electrical stimulation for more than 1 week. We also succeeded in preparing PEDOT microelectrodes on hydrogels like collagen and agarose, that shows surface resistivity of 50 Ω/□. The combination of these two hydrogel sheets, on which myotubes and PEDOT are micropatterned, provides a totally contractile biochip that will be a powerful tool for the muscle-targeted drug development.
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