2012 Fiscal Year Final Research Report
A neuropsychological study for resolution of pathology in the prefrontal dysfunction
| Project/Area Number |
20330141
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Clinical psychology
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| Research Institution | University of Toyama |
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Principal Investigator |
MATSUI Mie 富山大学, 大学院・医学薬学研究部, 准教授 (70209485)
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| Co-Investigator(Renkei-kenkyūsha) |
NOGUCHI Kyo 富山大学, 大学院・医学薬学研究部(医学), 准教授 (10242497)
SUZUKI Michio 富山大学, 大学院・医学薬学研究部(医学), 教授 (40236013)
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| Project Period (FY) |
2009 – 2012
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| Keywords | 認知障害 / 統合失調症 / 脳画像 / 神経心理学 / 前頭葉 |
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| Research Abstract |
It aimed at clarifying the neural base of pathology of prefrontal dysfunction centering on schizophrenia and the role of prefrontal function. This study suggests failure to use a semanticorganization strategy for memory in schizophrenia might be related to reduced volume in the inferior frontal gyrus. The difference of function between dorso-lateral and medial prefrontal area became more clear from memory function or control function using functional neuroimaging. Although patients with frontal lobe damage showed worse performance in neuropsychological tests, it was suggested that the functions to fall by damaged area differ.
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[Presentation] Age-related volumetric changes of prefrontal gray and white matter from healthy infants to adults.2010
Author(s)
Matsui, M., Tanaka, C., Niu, L., Matsuzawa, J., Noguchi, K., Miyawaki, T., Bilker, W.B. ,Wierzbicki, M., Gur, R.C.
Organizer
The 20thAnnual Rotman Research Institute Conference- "Frontal Lobes"
Place of Presentation
Toronto
Year and Date
20100322-26
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