2011 Fiscal Year Final Research Report
Versatile Molecular Devices Based on Functional DNA and PNA Complexes
| Project/Area Number |
20350038
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Kumamoto University |
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Principal Investigator |
IHARA Toshihiro 熊本大学, 大学院・自然科学研究科, 教授 (40253489)
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| Co-Investigator(Kenkyū-buntansha) |
SAKURAI Toshihiko 鳥取大学, 工学部, 准教授 (10332868)
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| Co-Investigator(Renkei-kenkyūsha) |
HAYASHIDA Osamu 福岡大学, 理学部, 教授 (20231532)
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| Project Period (FY) |
2008 – 2011
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| Keywords | DNAコンジュゲート / 協同性 / 化学センサー / バイオセンサー / 光化学 / 錯生成 / ハイブリダイゼーション / 機能性核酸 |
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| Research Abstract |
The research aims at the development of the DNA and PNA-based functional modules and their integrated flexible system for chemical or physical signal amplification and transduction. DNA conjugates carryingβ-cyclodextrin, terpyridine, and anthracene were prepared as functional modules for fluorescent SNP analysis, metallo-regulation of DNA functions, and reversible photo-regulation of DNA-based nanostructures, respectively.
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