2010 Fiscal Year Final Research Report
Cross-Coupling through Selective Cleavage of C-H and C-C Bonds
| Project/Area Number |
20350050
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SATOH Tetsuya 大阪大学, 工学研究科, 准教授 (40273586)
HIRANO Koji 大阪大学, 工学研究科, 助教 (70532696)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 合成化学 / クロスカップリング / 炭素結合 / 遷移金属触媒 / パイ共役分子 |
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| Research Abstract |
The coupling reaction of suitably functionalized aromatic and heteroaromatic substrates with aryl halides, alkenes, and alkynes proceeded effectively in the presence of a palladium or rhodium catalyst. Especially, aromatic carboxylic acids was found to undergo multi-coupling via C-H and C-C bond cleavages to afford structurally interesting pi-conjugated compounds. Furthermore, a number of C-H transformation reactions of aromatic compounds by using copper and nickel catalysts have been developed.
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