2011 Fiscal Year Final Research Report
One-step Synthesis and Polymerization of Glyco-monomers in Aqueous Media without Using Protecting Groups
| Project/Area Number |
20350051
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Polymer chemistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2008 – 2011
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| Keywords | 保護基 / 配糖化 / 糖質 / 一段階合成 |
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| Research Abstract |
Sugar molecules have many hydroxyl groups. In order to derivatize sugar molecules, the hydroxyl groups must be protected. In the present research, we have developed a completely different synthetic process of glycol-monomers without using any protecting groups in aqueous media. The resulting glyco-monomers can be utilized as starting materials of various glyco-polymers.
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[Journal Article] α-N-Acetylglalctosaminidase from Infant-associated Bifid bacteria Belonging to Novel Glycoside Hydrolase Family 129 is Implicated in Alternative Mucin Degradation Pathway2012
Author(s)
M. Kiyohara, T. Nakatomi, S. Kurihara, S. Fushinobu, H. Suzuki, T. Tanaka, S. Shoda, M. Kitaoka, T. Katayama, K. Yamamoto, H. Ashida
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Journal Title
J. Biol. Chem.
Volume: 287
Pages: 693-700
Peer Reviewed
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[Journal Article] Efficient transfer of sialo-oligosaccharide onto proteins by combined use of a glycosynthase-like mutant of Mucor hiemalis endoglycosidase and synthetic sialo-complex-type sugar oxazoline2010
Author(s)
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Journal Title
Biochim. Biophys. Acta
Volume: 1800
Pages: 1203-1209
Peer Reviewed
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[Journal Article] 4, 6-Dimethoxy-1, 3, 5-triazine oligoxyloglucans : Novel one-step preparable substrates for studying action of endo-.-1, 4-glucanase III from Trichoderma reesei2010
Author(s)
A. Kobayashi, T. Tanaka, K. Watanabe, M. Ishihara, M. Noguchi, H. Okada, Y. Morikawa, S. Shoda
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Journal Title
Bioorg. Med. Chem. Lett.
Volume: 20
Pages: 3588-3591
Peer Reviewed
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[Journal Article] 4, 6-Dimethoxy-1, 3, 5-triazin-2-yl .-D-glycosaminides : Novel Substrates for Transglycosylation Reaction Catalyzed by Exo-Dglucosaminidase from Amycolatopsis oriental is
Author(s)
T. Tanaka, T. Wada, M. Noguchi, M. Ishihara, A. Kobayashi, T. Ohnuma, T. Fukamizo, R. Brzezinski, S. Shoda
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Journal Title
J. Carbohydr. Chem
Volume: (印刷中)
Peer Reviewed
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