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2010 Fiscal Year Self-evaluation Report

Molecular Mechanism of Bio-mineralization of Orientated Aragonite Crystals in Mabe Pearl and Its Development to The Novel Photonic Nano-materials

Research Project

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Project/Area Number 20350073
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Chemistry related to living body
Research InstitutionTohoku University

Principal Investigator

OGAWA Tomohisa  Tohoku University, 大学院・生命科学研究科, 准教授 (80240901)

Project Period (FY) 2008 – 2011
Keywordsバイオミネラリゼーション / 自己組織化 / レクチン / X線構造解析 / 結晶配向性
Research Abstract

(1)マベガイ真珠バイオミネラリゼーションのアラゴナイト結晶の3軸配向性制御に関わるタンパク質の機能解析
(2)アラゴナイト結晶形成反応における動態、構造変化、相互作用解析
(3)マベガイ真珠バイオミネラリゼーション関連タンパク質の立体構造解析
(4)マベガイ真珠バイオミネラリゼーション関連タンパク質のリコンビナント発現
(5)真珠アラゴナイト結晶3軸配向性分子メカニズムのタンパク工学による制御

  • Research Products

    (11 results)

All 2011 2010 2009 2008

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (5 results) Book (1 results)

  • [Journal Article] Tracing Protein Evolution through Ancestral Structures of Fish Galectin Structure2011

    • Author(s)
      A.Konno, A.Kitagawa, M.Watanabe, T.Ogawa, T.Shirai
    • Pages
      doi : 10.1016/.str.2011.02.014
    • Peer Reviewed
  • [Journal Article] Protein engineering of conger eel galectins by tracing of molecular evolution using probable ancestral mutants.2010

    • Author(s)
      A.Konno, S.Yonemaru, A.Kitagawa, K.Muramoto, T.Shirai, T.Ogawa
    • Journal Title

      BMC Evolutionary Biology 10:43

      Pages: doi : 10.1186/1471-2148-10-43.

    • Peer Reviewed
  • [Journal Article] Evaluation of silica gel-immobilized phosphorylcholine columns for size exclusion chromatography and their application in the analysis of the subunit structures of fish-egg lectins.2009

    • Author(s)
      Y.Watanabe, M.Abolhassani, Y.Tojo, Y.Suda, K.Miyazawa, Y.Igarashi, K.Sakuma, T.Ogawa, K.Muramoto
    • Journal Title

      J.Chromatography A 1216(48)

      Pages: 8563-8566

    • Peer Reviewed
  • [Journal Article] Structure of Rhamnose-binding Lectin CSL3 : Unique Pseudo-tetrameric Architecture of a Pattern Recognition Protein.2009

    • Author(s)
      Shirai T., Watanabe Y., Lee M.-s., Ogawa T., Muramoto K.
    • Journal Title

      J.Mol.Biol. 391(2)

      Pages: 390-403

    • Peer Reviewed
  • [Journal Article] A novel recombinant system for functional expression of myonecrotic snake phospholipase A_2 in escherichia coli using a new fusion affinity tag.2008

    • Author(s)
      M.Seto, T.Ogawa, K.Kodama, K.Muramoto, Y.Kanayama, Y.Sakai, T.Chijiwa, M.Ohno
    • Journal Title

      Protein Exp.Purif. 58(2)

      Pages: 194-202

    • Peer Reviewed
  • [Presentation] マベガイADPリボシルトランスフェラーゼタンパク質による真珠アラゴナイト形成機構の解析(Molecular mechanism of aragonite crystal formation by ADP ribosyltransferase proteins from Pteria penguin pearl shell)2010

    • Author(s)
      小川智久, 荒川香織, 堀田俊英, 永沼孝子, 村本光二, 渡辺精一, 谷内哲夫, 吉見享祐
    • Organizer
      BMB2010第33回日本分子生物学会年会/第83回日本生化学会大会合同大会
    • Year and Date
      20101207-20101210
  • [Presentation] タンパク質による真珠バイオミネラリゼーション制御の分子メカニズム2010

    • Author(s)
      小川智久、荒川香織、堀田英俊, 永沼孝子、村本光二、渡辺精一, 白石孝信, 尾定誠, 谷内哲夫, 吉見享佑
    • Organizer
      平成22年度化学系学協会東北大会
    • Place of Presentation
      岩手大学工学部
    • Year and Date
      20100925-26
  • [Presentation] A novel recombinant system for efficient expression of unstable proteinsusing a new fusion affinity tag and high-performance cleavage enzyme2010

    • Author(s)
      Tomohisa Ogawa
    • Organizer
      第3回タンパク質-ペプチド会議Pepcon-2010
    • Place of Presentation
      中国北京
    • Year and Date
      2010-03-22
  • [Presentation] ADP ribosyl transferases regulate the aragonite crystal orientation and formation in the biomineralization of Pteria penguin pearl shell2009

    • Author(s)
      Tomohisa Ogawa, Kaori Arakawa, Takako Naganuma, Kyosuke Yoshimi, Koji Muramoto
    • Organizer
      第2回スイス-日本 生命化学シンポジウム
    • Place of Presentation
      東京大学
    • Year and Date
      20090911-20090912
  • [Presentation] JACALIN-LIKE MULTIPLE LECTINS RELATED TO BIOMINERALIZATION OF PTERIA PENGUIN PEARL SHELL2008

    • Author(s)
      Tomohisa Ogawa, Takako Naganuma, Wataru Hoshino, Rie Sato, Yukihiro Shikanai, Koji Muramoto, Kyosuke Yoshimi, Makoto Osada
    • Organizer
      Interlec23
    • Place of Presentation
      Universities of Edinburgh and Stirling, UK
    • Year and Date
      20080711-20080716
  • [Book] Ribosomal Proteins and Protein Engineering : ISBN:978-1-60741-005-8 (Ed.Ortendhal & Salchow ANCESTRAL PROTEIN RECONSTRUCTION AS A NEW FIELD IN PROTEIN ENGINEERING)2010

    • Author(s)
      A.Konno, T.Ogawa, T.Shirai
    • Publisher
      Nova Science Publishers, Inc.

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Published: 2012-02-13   Modified: 2016-04-21  

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