2010 Fiscal Year Final Research Report
Advances in Studies on Multicopper Reductases
| Project/Area Number |
20350078
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemistry related to living body
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NOJIRI Masaki 大阪大学, 大学院・理学研究科, 助教 (20333346)
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| Co-Investigator(Renkei-kenkyūsha) |
SAKURAI Takeshi 金沢大学, 大学院・自然科学研究科, 教授 (90116038)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 亜硝酸還元酵素 / 銅タンパク質 / 脱窒菌 / ニキビ菌 / 海洋性好冷菌 / X線結晶構造解析 |
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| Research Abstract |
For the biological and environmental importance, there have been many reports on Cu-containing nitrite reductases (NIRs), which are trimers containing two copper ions in each monomer. We have recently found new hexameric and trimeric NIRs having an extra domain at the N- and C-terminus, respectively. In this project, the structure-function relationships of the new NIRs from a propionibacterium and a marine psychrophilic bacterium have been studied.
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