2010 Fiscal Year Final Research Report
Generation of multi-pulse laser-Compton X-rays and their application to real-time medical imaging technology
| Project/Area Number |
20360043
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied physics, general
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
YAMADA Kawakatsu National Institute of Advanced Industrial Science and Technology, 計測フロンティア研究部門, 副研究部門長 (70358258)
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| Co-Investigator(Kenkyū-buntansha) |
TOYAKAWA Hiroyuki 独立行政法人産業技術総合研究所, 計測フロンティア研究部門, 研究グループ長 (80357582)
KURODA Ryunosuke 独立行政法人産業技術総合研究所, 計測フロンティア研究部門, 研究員 (70350428)
YASUMOTO Masato 独立行政法人産業技術総合研究所, 計測フロンティア研究部門, 主任研究員 (60358207)
IKEURA Hiromi 独立行政法人産業技術総合研究所, 計測フロンティア研究部門, 主任研究員 (90357319)
KOIKE Masaki 独立行政法人産業技術総合研究所, 計測フロンティア研究部門, 研究グループ長 (00356958)
AOYAMA Takahiko 名古屋大学, 医学部, 教授 (80023307)
FUKUYAMA Naoto 東海大学, 医学部, 准教授 (50349338)
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| Co-Investigator(Renkei-kenkyūsha) |
MORI Hidezo 東海大学, 医学部, 教授 (90146598)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 加速器 / 高出力レーザー / レーザーコンプトン散乱 / 単色X線 / 放射線 / 量測定・評価 / 医用・生体画像 / 画像診断システム |
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| Research Abstract |
X-rays produced through the laser-Compton scattering process (LCS X-rays) are expected to be a promising tool for fine and low-dose imaging in biology or medicine due to their partially-spatial coherence and quasi-monochromaticity. Here we studied an original method, namely "multi-pulse LCS", to increase the X-ray yield to a level sufficient for such an X-ray imaging technology. In this method, 100-bunch electron beams generated in a photo-cathode RF gun and accelerated by a compact linac collide with laser pulses accumulated inside a specially-designed regeneratively amplifying laser resonator. Preliminary experiments for the medical imaging were performed using LCS X-rays, based on the phase-contrast and K-edge-contrast schemes, which will enable us not only to take a still shot of dynamic behavior in organs but also to achieve a real-time motion picture using successively-obtained single-shot images. By using a human-body phantom, it was also found that the X-ray dose in such an LCS X-ray imaging process is sufficiently low.
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