2010 Fiscal Year Final Research Report
Ion transport control of cell membrane by developing sensing technique using evanescent wave for refractive index and electrostatic potential of cell
| Project/Area Number |
20360102
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thermal engineering
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| Research Institution | Keio University |
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Principal Investigator |
SATO Yohei Keio University, 理工学部, 准教授 (00344127)
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| Co-Investigator(Kenkyū-buntansha) |
MURAKAMI Toshiyuki 慶應義塾大学, 理工学部, 教授 (00255598)
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| Project Period (FY) |
2008 – 2010
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| Keywords | マイクロ流体デバイス / 細胞表面電位 / 細胞内屈折率 / エバネッセント波 / マイクロPIV / マイクロLIF |
|---|
| Research Abstract |
A non-invasive sensing technique using evanescent wave for the refractive index and electrostatic potential of cell was developed in order to control ion transport between cell and culture solution in microfluidic device. A novel technique to detect refractive index difference was proposed utilizing light scattering by evanescent wave illumination. A color imaging of electrostatic potential distribution was achieved by developing a two-color LIF technique.
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Research Products
(10 results)
