2012 Fiscal Year Final Research Report
Structural study of the torque-generating unit in the bacterial flagellar motor
Project/Area Number |
20370064
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Biophysics
|
Research Institution | The Institute of Physical and Chemical Research |
Principal Investigator |
YONEKURA Koji 独立行政法人理化学研究所, 米倉生体機構研究室, 准主任研究員 (50346144)
|
Co-Investigator(Kenkyū-buntansha) |
MAKI-YONEKURA Saori 独立行政法人理化学研究所, タンパク質結晶構造解析研究グループ, 研究員 (20513386)
|
Project Period (FY) |
2008 – 2012
|
Keywords | 構造生物学 / イオンチャネル / べん毛モーター / 電子顕微鏡 / X 線結晶構造解析 |
Research Abstract |
The bacterial flagellum is a rotary motor powered by the electrochemical potential of specific ions across the cytoplasmic membrane. There is little information about its working mechanism of this biological motor, the information which could be useful for biological science and nano-technology. In Vibrio, an inner membrane complex, PomAB, converts Na+ flux into rotation of the flagellum. We have been studying the structure of PomAB by X-ray crystallography and cryo-electron microscopy to elucidate the working mechanism of this energy conversion system.
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Research Products
(11 results)