2010 Fiscal Year Final Research Report
Studies on the functions and the molecular dynamics of chitin synthases with a myosin motor-like domain
| Project/Area Number |
20380045
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied microbiology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
HORIUCHI Hiroyuki 東京大学, 大学院・農学生命科学研究科, 准教授 (00209280)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 微生物 / バイオテクノロジー / 糸状菌 / Yarrowia / 細胞壁 |
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| Research Abstract |
Some fungal chitin synthases have a myosin motor-like domain in their N-termini. We analyzed the functions of these chitin synthases using a model filamentous fungus Aspergillus nidulans and a dimorphic yeast Yarrowia lipolytica.
In Y. lipolytica, these chitin synthases were suggested to function in maintaining the cell wall integrity. We also isolated the proteins that may interact with these chitin synthases and analyzed their functions in A. nidulans.
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