Longitudinal genetic epidemiological study for cardiovascular diseases based on Japanese general population participated in medical check-up process of Ehime University Anti-aging doc.

2010 Fiscal Year Self-evaluation Report

• Project/Area Number: 20390185
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Kyoto University (2012); Ehime University (2008-2011)
• Principal Investigator: TABARA Yasuharu Ehime University, 大学院・医学系研究科, 講師 (00268749)
• Project Period (FY): 2008 – 2012
• Keywords: 動脈硬化 / 長期縦断疫学研究 / ゲノム / 動脈硬化性疾患

Research Abstract

愛媛大学医学部附属病院に申請者らが開設した"抗加齢ドック"受診者を対象に、脳卒中・虚血性心疾患・転倒・骨折・死亡に関する長期縦断疫学研究を行い、当該疾患や予後に影響する因子を横断的/縦断的解析から明確化する。

Research Products

• [Journal Article] Association of four genetic loci with uric acid levels and reduced renal function : the J-SHIPP Suita study. (2010)
  • Author(s): Tabara Y, Kohara K, Kawamoto R, Hiura Y, Nishimura K, Morisaki T, Kokubo Y, Okamura T, Tomoike H, Iwai N, Miki T.
  • Journal Title: Am J Nephrol. 32 Pages: 279-286
  • Peer Reviewed
• [Journal Article] Postural instability is associated with brain atrophy and cognitive impairment in the elderly : the J-SHIPP study. (2010)
  • Author(s): Kido T, Tabara Y, Igase M, Ochi N, Uetani E, Nagai T, Yamamoto M, Taguchi K, Miki T, Kohara K.
  • Journal Title: Dement Geriatr Cogn Disord. 29 Pages: 379-387
  • Peer Reviewed
• [Journal Article] Abnormal nocturnal blood pressure profile is associated with mild cognitive impairment in the elderly : the J-SHIPP study. (2010)
  • Author(s): Guo H, Tabara Y, Igase M, Yamamoto M, Ochi N, Kido T, Uetani E, Taguchi K, Miki T, Kohara K.
  • Journal Title: Hypertens Res. 33 Pages: 32-36
  • Peer Reviewed
• [Journal Article] Composition of lower extremity in relation to a high ankle-brachial index. (2009)
  • Author(s): Tabara Y, Igase M, Kido T, Ochi N, Miki T, Kohara K.
  • Journal Title: J Hypertens. 27 Pages: 167-173
  • Peer Reviewed
• [Journal Article] Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening. (2009)
  • Author(s): Tabara Y, Osawa H, Kawamoto R, Onuma H, Shimizu I, Miki T, Kohara K, Makino H.
  • Journal Title: Diabetes. 58 Pages: 493-498
  • Peer Reviewed
• [Presentation] Association of the functional variant in the HMGCR with LDL cholesterol in Japanese. (2010)
  • Author(s): Tabara Y, Hiura Y, Kokubo Y, Okamura T, Goto Y, Nonogi H, Miki T, Tomoike H, Iwai N.
  • Organizer: The Genomics of Common Diseases.
  • Place of Presentation: Huston, USA
  • Year and Date: 20101006-20101009
• [Presentation] Class effects of BP-lowering drugs on central blood pressure measurement. (2010)
  • Author(s): Uetani E, Tabara Y, Igase M, Kido T, Ochi N, Kohara K, Miki T.
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension.
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 20100926-20100930
• [Presentation] Postprandial hypotension as a risk factor for cognitive decline in community-dwelling elderly persons. (2010)
  • Author(s): Uetani E, Tabara Y, Igase M, Kido T, Ochi N, Yamamoto M, Kohara K, Miki T.
  • Organizer: 23rd Scientific Meeting, The International Society of Hypertension.
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 20100926-20100930
• [Presentation] Postprandial hypotension is associated with asymptomatic cerebrovascular damage in community-dwelling elderly. (2009)
  • Author(s): Tabara Y, Igase M, Nagai T, Kido T, Ochi N, Uetani E, Miki T, Kohara K.
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics.
  • Place of Presentation: Paris, France
  • Year and Date: 20090705-20090709
• [Presentation] Postural instability is-associated with brain atrophy and cognitive impairment in elderly : the J-SHIPP study. (2009)
  • Author(s): Kido T, Tabara Y, Igase M, Ochi N, Uetani E, Nagai T, Yamamoto M, Taguchi K, Kohara K, Miki T.
  • Organizer: XIXth IAGG World Congress of Gerontology and Geriatrics.
  • Place of Presentation: Paris, France
  • Year and Date: 20090705-20090709