2010 Fiscal Year Final Research Report
Immune and inflammatory mechanism relationship between psychosocial factors and health outcomes
Project/Area Number |
20390190
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Public health/Health science
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Research Institution | Tokyo Metropolitan Institute of Gerontology |
Principal Investigator |
FUJIWARA Yoshinori Tokyo Metropolitan Institute of Gerontology, 東京都健康長寿医療センター研究所, 研究副部長 (50332367)
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Co-Investigator(Renkei-kenkyūsha) |
SHINKAI Shoji 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (60171063)
YOSHIDA Hiroto 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (40415493)
KOBAYASHI Erika 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 主任研究員 (10311408)
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Project Period (FY) |
2008 – 2010
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Keywords | 疫学 / 心理社会変数 |
Research Abstract |
We conducted medical examination in Kusatsu town in 2008. Subjects of the cross-sectional were five hundred and seventy one older persons aged 65 years and over who participated in the medical examination. The present study demonstrated that several kinds of immune and inflammatory biomarkers were significantly associated with psychosocial factors such as school years and self-rated health after adjustment for confounding variables. Also, we obtained the data of 379 older subjects for this study from the Tokyo Metropolitan Institute of Gerontology-Longitudinal Interdisciplinary Study on Aging (TMIG-LISA) in Koganei city in 1991. Psychological variables such as self-rated health and life satisfaction index K predicted changes in immune and inflammatory biomarkers such as IL-6 and white blood cell after 4 years
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Research Products
(25 results)
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[Presentation] Brief screening tool for mild cognitive impairment in older Japanese : validation of the Japanese version of the Montreal Cognitive Assessment (MoCA-J).2009
Author(s)
Fujiwara Y, Suzuki H, Yasunaga M, Sugiyama M, Ijuin M, Sakuma N, Iwasa H, Shinkai S
Organizer
The Gerontological Society of America, 62nd Annual Scientific Meeting.
Place of Presentation
Atlanta, GA, USA
Year and Date
20091118-20091122
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[Remarks] ホームページ等