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2010 Fiscal Year Self-evaluation Report

Translational research for establishment of heavy ion radiotherapy for cancer

Research Project

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Project/Area Number 20390324
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionGunma University

Principal Investigator

NAKANO Takashi  Gunma University, 大学院・医学系研究科, 教授 (20211427)

Project Period (FY) 2008 – 2011
Keywords重粒子線 / 放射線治療 / 放射線生物学 / 粒子線治療 / 放射線腫瘍学
Research Abstract

本研究は重粒子線治療の革新的展開のた晩のトランスレーショナル研究を、i)重粒子紡治療の最適な分割効果や費用対効果の研究、ii)重粒子線治療による細胞死や抗癌剤僧用効果の研究、iii)脳機能ならびに脳腫瘍に対する重粒子線による照射効果に関する研究、の3サブ課題に分けて展開し、重粒子紡に特徴的な生物効果を基礎研究から解明し、さらに臨床データの解析から科学的に検記し、どのような腫瘍が真に重粒子線治療の遥応となるかを明らかにするとともに、最適な治療方法を開拓する基礎的-臨床的研究を行う。

  • Research Products

    (9 results)

All 2010 2009 2008

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (2 results)

  • [Journal Article] Current Advancement in Radiation Therapy for Uterine Cervical Cancer.2010

    • Author(s)
      Nakano T, Ohno T, Ishikawa H, Suzuki Y, Takahashi T.
    • Journal Title

      J.Radiat. Res. 51

      Pages: 1-8

    • Peer Reviewed
  • [Journal Article] Cost-effectiveness of carbon ion radiation therapy for locally recurrent rectal cancer.2010

    • Author(s)
      Mobaraki A, Ohno T, Yamada S, Sakurai H, Nakano T.
    • Journal Title

      Cancer Sci. 101

      Pages: 1834-1839

    • Peer Reviewed
  • [Journal Article] Combining Carbon Ion Radiotherapy and Local Injection of α-Galactosylceramide-Pulsed Dendritic Cells Inhibits Lung Metastases in an In Vivo Murine Model.2010

    • Author(s)
      Ohkubo Y, Iwakasya M, Seion K, Nakawtari M,_Wada H, Kaimijuku_H, Nakamra_E,_Nakano T, Imai T.
    • Journal Title

      Int J Radial Oncol Biol Pbys. 78

      Pages: 1524-31

    • Peer Reviewed
  • [Journal Article] Prognostic impact of mitotic index of proliferating cell populations in cervical cancer patients treated with carbon ion beam.2009

    • Author(s)
      Suzuki Y, Oka K, Ohno T, Kato S, Tsujii H, Nakano T.
    • Journal Title

      Cancer. 115(9)

      Pages: 1875-1882

    • Peer Reviewed
  • [Journal Article] Adverse effects of androgen deprivation therapy on persistent genitourinary complications after carbon ion radiotherapy for prostate cancer.2008

    • Author(s)
      Ishikawa H, Tsuji H, Kamada T, Hirasawa N, Yanagi T, Mizoe JE, Akakura K, Suzuki H, Shimazaki J, Nakano T, Tsujii H
    • Journal Title

      Int J Radiat Oncol Biol Phys 72(1)

      Pages: 78-84

    • Peer Reviewed
  • [Journal Article] Comparison of the radiobiological effect of carbon ion beam therapy and conventional radiation therapy on cervical cancer.2008

    • Author(s)
      Suzuki Y, Nakano T, Ohno T, Oka K
    • Journal Title

      J Radial Res(Tokyo) 49(5)

      Pages: 473-479

    • Peer Reviewed
  • [Journal Article] Quality of life in men treated with carbon ion therapy for prostate cancer International.2008

    • Author(s)
      Wakatsuki M, Tsuji H, Ishikawa H, Yanagi T, Kamada T, Nakano T, Suzuki H, Akakura K, Shimazaki J, Tsujii H
    • Journal Title

      Int J Radiat Oncol Biol Phys 72

      Pages: 1010-1015

    • Peer Reviewed
  • [Presentation] がん研究入門コース「がんに対する新しい放射線治療戦略」2010

    • Author(s)
      中野隆史
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      リーガロイヤルホテル大阪
    • Year and Date
      2010-09-24
  • [Presentation] がんプロフェッショナルの検証と提言~2年間を振り返る2009

    • Author(s)
      中野隆史
    • Organizer
      第47回日本癌治療学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-22

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Published: 2012-02-13   Modified: 2016-04-21  

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