2010 Fiscal Year Final Research Report
New therapeutic approach for glaucoma via drug-mediated bleb regulation
| Project/Area Number |
20390449
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Kumamoto University |
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Principal Investigator |
TANIHARA Hidenobu Kumamoto University, 大学院・生命科学研究部, 教授 (60217148)
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| Co-Investigator(Kenkyū-buntansha) |
INATANI Masaru 熊本大学, 医学部附属病院, 講師 (40335245)
KAWAJI Takahiro 熊本大学, 医学部附属病院, 講師 (30423677)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 眼薬理学 / 創傷治癒 |
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| Research Abstract |
We identified risk factors for surgical failure of trabeculectomy, a major surgery for glaucoma patients. In open-glaucoma patients, previous cataract surgery is a significant risk factor for the surgical failure while previous cataract surgery and granulomatous uveitis-type are risk factors in uveitic glaucoma patients. An anti-VEGF drug, bevacizumab, reduces surgical complications, and improves the short-term surgical success of trabeculectomy.
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[Presentation] Trabeculectomy with mitomyci C for open-angle glaucoma in phakic eyes vs. pseudophakic eyes after phacoemulsification.2010
Author(s)
Takihara Y, Inatani M, Seto T, Iwao K, Iwao M, Inoue T, Kasaoka N, Murakami A, Futa R, Tanihara H
Organizer
The Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) Convention Center
Place of Presentation
Fort Lauderdale, Florida, USA
Year and Date
20100502-20100506
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