2010 Fiscal Year Final Research Report
The development of non-surgical preprosthodontic bone augmentation procedure for the strategic prosthodontic treatment
| Project/Area Number |
20390490
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Prosthetic dentistry
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
AYUKAWA Yasunori Kyushu University, 大学病院, 講師 (50304697)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OGINO Yoichiro 九州大学, 大学病院, 助教 (50380431)
KOYANO Kiyoshi 九州大学, 大学院・歯学研究院, 教授 (50195872)
ATSUTA Ikiru 九州大学, 大学院・歯学研究院, 助教 (30423487)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | 補綴前骨再生 / トップダウントリートメント / インプラント |
|---|
| Research Abstract |
The aim of this study was to achieve preprosthodontic bone augmentation without using artificial, exogenous or autogenous bone substitute. Among several drug delivery systems, a compound consisted of atelocollagen and alpha-TCP, and poly (lactic-co-glycolic acid) (PLGA) were superior to others from the point of view of persistence and sustained-release capability of statin, a bone promotive drug. Both statin-collagen-TCP complex and statin-impregnated PLGA had a promotive effect on osteoblastic cell differentiation in vitro, and they had a bone formation capacity in rat model.
|
Research Products
(8 results)
