2010 Fiscal Year Final Research Report
Changes in GABA signaling during development and regeneration
| Project/Area Number |
20500310
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | University of the Ryukyus |
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Principal Investigator |
TAKAYAMA Chitoshi University of the Ryukyus, 大学院・医学研究科, 教授 (60197217)
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| Project Period (FY) |
2008 – 2010
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| Keywords | GABA / GABA transporters / KCC2 / spinal cord / development / brain stem / regeneration / immunohistochemistry |
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| Research Abstract |
To reveal the GABAergic roles in development, regeneration and maintenance of plasticity in the nervous system, we examined the changes in expression and localization of various molecules involved in GABAergic transmission. Excitatory action of GABA might play important roles in development of nervous system except for anterior horn of spinal cord, regeneration of the hypoglossal nerve, and maintenance of plasticity in the somatosensory cortex.
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