2010 Fiscal Year Final Research Report
Two steps screening of autistic genes by using Fly/mouse as model animals.
Project/Area Number |
20500323
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Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Nerve anatomy/Neuropathology
|
Research Institution | Kanazawa University |
Principal Investigator |
KOIZUMI Keita Kanazawa University, 子どものこころの発達研究センター, 特任准教授 (70377406)
|
Co-Investigator(Kenkyū-buntansha) |
HIGASHIDA Haruhiro 金沢大学, 医学系, 教授 (30093066)
|
Co-Investigator(Renkei-kenkyūsha) |
MUNESUE Toshio 金沢大学, 子どものこころの発達研究センター, 特任教授 (50293353)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 脳発達障害 / 遺伝子スクリーニング |
Research Abstract |
The final goal of this study is to identify new genes that are associated with autism/developmental disorders. For this purpose, we screened around 8800 genes in Drosophila as the first step and the second step studies in mice picked up 7 candidate genes, possibly, related to human developmental disorders. Our clinical study finally succeeded to figure out ones of these genes, RoboIII/IV are associated with autism.
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