2010 Fiscal Year Final Research Report
Development and Assessment of tomosynthesis reconstruction algorithm based on refraction contrast
| Project/Area Number |
20500385
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Yamagata University |
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Principal Investigator |
YUASA Tetsuya Yamagata University, 大学院・理工学研究科, 教授 (30240146)
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| Co-Investigator(Renkei-kenkyūsha) |
ANDO Masami 東京理科大学, 教授 (30013501)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 放射光X線 / 屈折コントラスト / トモシンセシス |
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| Research Abstract |
A novel tomosynthesis imaging system for soft tissues using Laue-case analyzer is described. Since the imaging system obtains angular deviation by refraction from the projections simultaneously acquired in forwardly diffracted and diffracted directions, the measurement time as well as the radiation dose required decreases by one half compared to the conventional diffraction enhanced imaging (DEI) method. In addition, the proposed reconstruction algorithm derived from the quantitative relationship in measurement process produces images in no way inferior to refraction-contrast CT images from the viewpoint of morphological imaging in spite of one tenth the radiation dose of refraction-contrast CT imaging. We ex vivo imaged a lung tissue sample excised from a human using the system constructed at the vertical wiggler beamline PF-BL14C in KEK to demonstrate the efficacy of the proposed imaging protocol.
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Research Products
(16 results)
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[Journal Article] Investigation of the distribution of elements in snail shell with the use of synchrotron-based, micro-beam X-ray fluorescence spectrometry2009
Author(s)
D.V.Rao, M.Swapna, R.Cesareo, A.Brunetti, T.Akatsuka, T.Yuasa, T.Takeda, G.Tromba, G.E.Gigante
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Journal Title
Journal of Trace Elements in Medicine and Biology Vol.23, Iss.4,
Pages: 251-257
Peer Reviewed
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[Journal Article] Refraction-based 2D, 2.5D and 3D medical imaging : Stepping forward to a clinical trial2008
Author(s)
M.Ando, H.Bando, T.Endo, S.Ichihara, E.Hashimoto, K.Hyodo, T.Kunisada, G.Li, A.Maksimenko, K.Mori, D.Shimao, H.Sugiyama, T.Yuasa, E.Ueno
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Journal Title
European Journal of Radiology Vol.68S
Pages: S32-S36
Peer Reviewed
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[Journal Article] 3-D Reconstruction of High-Grade Ductal Carcinoma In Situ of the Breast with Casting Type Calcifications using Refraction-Based X-Ray CT2008
Author(s)
S.Ichihara, M.Ando, E.Hashimoto, A.Maksimenko, H.Sugiyama, C.Ohbayashi, T.Yuasa, K.Yamasaki, Y.Arai, K.Mori, T.Endo
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Journal Title
Virchows Archiv Vol.452, No.1
Pages: 41-47
Peer Reviewed
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