2010 Fiscal Year Final Research Report
Quantitative evaluation of small spherical structures in PSF-based CT image simulation
| Project/Area Number |
20500389
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Niigata University |
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Principal Investigator |
OHKUBO Masaki Niigata University, 医歯学系, 准教授 (10203738)
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| Co-Investigator(Renkei-kenkyūsha) |
WADA Shinichi 新潟大学, 医歯学系, 教授 (80105519)
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| Research Collaborator |
MATSUMOTO Toru , 健生クリニック
MURAO Kohei , 富士通(株)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 点広がり関数(PSF) / X線CT装置 / 変調伝達関数(MTF) / 空間分解能 |
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| Research Abstract |
A technique of three-dimensional (3D) CT image simulation based on the point spread function (PSF) was developed. We simulated CT images from the object functions of ideal spheres, assuming solitary pulmonary nodules, and calculated the sphere volumes with a simple threshold technique in which the relationship between the threshold and the volume was analyzed. We determined the threshold (defined as T') so that the sphere volume obtained in simulated image was equal to its object function (true volume). It was quantitatively shown that the T' changed with the object sphere diameter, the image reconstruction kernel, slice thickness and slice location while maintaining a constant density in the object. Our simulation technique and present results will be effective for basic research on 3D nodule analysis.
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